Korea Brain Research Institute

Exploring the potential of AI-driven brain–computer interfaces for Alzheimer’s disease: an integrated framework for diagnosis and therapeutic intervention

Early diagnosis and timely intervention are critical in Alzheimer's disease (AD), yet conventional assessments fail to capture longitudinal neural dynamics. Although traditional biomarker frameworks offer essential pathological insights, they remain constrained by high costs and...

Atypical sensory traits and changes in white matter microstructures connected to the amygdala and hippocampus of the autistic brain

Abstract Aim Autism spectrum disorder (ASD) is characterized by atypical sensory traits. Understanding whether these traits of individuals with ASD are associated with white matter fiber tracts connected to these subcortical structures may be important; however, this relationship...

Mosapride promotes internalization of a TREK1–HTR4 complex and exerts rapid antidepressant-like effects

Major depressive disorder (MDD) remains a critical global health burden, and a substantial proportion of patients exhibit insufficient responses to conventional monoaminergic antidepressants. Selective inhibition of the two-pore domain potassium channel TREK1 has emerged as a pro...