Konyang University Hospital

Relative Contributions of Quinolone Resistance-Determining Region Mutations and Efflux Pump-Associated Mechanisms to Fluoroquinolone Resistance in Staphylococcus aureus Clinical Isolates and Their Associations with Virulence Gene Profiles

Background: Fluoroquinolone resistance in methicillin-resistant Staphylococcus aureus (MRSA) involves multiple mechanisms, including quinolone resistance-determining region (QRDR) mutations and efflux pump activity. However, the relationship between these resistance mechanisms an...

Extended treatment duration and recurrence in successfully treated drug-susceptible pulmonary tuberculosis with cavity on chest radiograph

Background Cavity on chest radiograph is recognized as an independent risk factor for recurrence in pulmonary tuberculosis (TB), but evidence supporting extended treatment in these patients remains limited, particularly in real-world data from Korea. Methods We performed a retros...

Development of a customized three-dimensional bolus using transparent gel wax and its application in electron beam therapy

Abstract Purpose: This study aimed to develop a customized bolus using commercially available transparent gel wax (TGW) without requiring 3D printing technology and to evaluate its applicability in radiotherapy, including its physical and dosimetric characteristics. Methods: A de...

Integrative Genomic Analysis Reveals Molecular and Clinical Disparities between Bladder and Upper Tract Urothelial Carcinoma in K-MASTER Program

Purpose: The clinical outcome of urothelial carcinoma presents significant variability, reflecting its molecular composition, epidemiologic attributes, and primary site of origin. Despite histological similarities, upper tract urothelial carcinoma (UTUC) and bladder urothelial ca...