Konkuk University Medical Center

Evaluating Immunotherapy Outcomes in Elderly Patients with Extensive-Stage Small-Cell Lung Cancer (KCSG LU23-15)

PurposeChemoimmunotherapy has improved outcomes in extensive-stage small-cell lung cancer (ES-SCLC), but its benefit in older adults remains uncertain because this population is underrepresented in clinical trials.We evaluated the real-world efficacy of first-line atezolizumab pl...

Early On-Treatment Host Fitness Dynamics Refine Prognostic Stratification in Advanced NSCLC Receiving First-Line Immunotherapy

PurposeWe assessed whether baseline and early on-treatment measurements of host fitness using the Prognostic Nutritional Index (PNI) provide complementary prognostic information in advanced non-small cell lung cancer (NSCLC). Materials and MethodsWithin the prospective, multicent...

Blood viscosity is associated with smoking status rather than the presence of chronic obstructive pulmonary disease: findings from the Korea COPD Subgroup Study (KOCOSS)

Abstract Background The relationship between smoking and blood viscosity is well established. However, the role of blood viscosity in the development of chronic obstructive pulmonary disease (COPD) and its impact on lung function decline remains unclear. Therefore, we aimed to in...

Integrative Genomic Analysis Reveals Molecular and Clinical Disparities between Bladder and Upper Tract Urothelial Carcinoma in K-MASTER Program

Purpose: The clinical outcome of urothelial carcinoma presents significant variability, reflecting its molecular composition, epidemiologic attributes, and primary site of origin. Despite histological similarities, upper tract urothelial carcinoma (UTUC) and bladder urothelial ca...

Absolute knee extensor strength, not limb symmetry, predicts outcomes and defines a rehabilitation threshold after medial opening‐wedge high tibial osteotomy

Abstract Purpose To identify a clinically relevant body mass‐normalised knee extensor strength threshold after high tibial osteotomy (HTO) and examine how absolute strength and limb symmetry index (LSI) relate to patient‐reported outcomes (PROMs), dynamic balance and longitudinal...

Pharmacologic Treatment Response in Panic Disorder with Comorbid Medical Conditions: A Systematic and Narrative Review

Panic disorder frequently co-occurs with medical conditions, complicating diagnosis and treatment.Although pharmacotherapy is a first-line treatment for panic disorder, pharmacotherapeutic evidence for patients with medical comorbidities is limited.Therefore, this review systemat...