Konkuk University Medical Center

White Blood Cell Counting in Severely Leukopenic Samples on a Sysmex XN Hematology Analyzer: Analytical Performance Evaluation of Whole Blood Mode and Low White Blood Cell Mode

Background: /L. Methods: Precision of WBC quantification in the two modes was evaluated using four samples according to the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) criterion (CV% 5.6). Linearity was evaluated at five concentrations. The two modes...

Perspectives on Community-Based Pediatric Obesity Prevention and Management Programs in South Korea: A Qualitative Interview Study of School and Local Public Health Center Providers

Background: Pediatric obesity has increased globally, and South Korea has reported the highest prevalence in East Asia. Despite national policies addressing children's nutrition and health, fragmented governance and overlapping programs may limit their effectiveness. We compared...

Long-Term Outcomes According to a Device-Assisted Enteroscopy Strategy after Capsule Endoscopy in Patients with Small Bowel Bleeding: A Nationwide Population-Based Cohort Study

Background/Aims: Although the use of device-assisted enteroscopy (DAE) has increased, few large-scale studies have examined long-term outcomes focused on small bowel (SB) bleeding. We analyzed National Health Insurance Service data to evaluate the clinical utility of DAE in patie...

Criteria-based probable REM sleep behaviour disorder and risk of Lewy body dementia: analyses of a memory clinic cohort and a community cohort

Abstract Background REM sleep behaviour disorder (RBD) is the strongest prodromal marker of alpha-synucleinopathies, but whether a brief questionnaire carries prognostic information for Lewy body dementia is unclear. We tested whether criteria-based probable RBD (pRBD)—a question...

Evaluating In-Vehicle Drunk-Driving Warning Symbols Using Generative AI: A Comparison with Human Judgments

This study examined whether Generative Artificial Intelligence (AI) can evaluate in-vehicle drunk-driving warning symbols (telltales) in ways comparable to human perceptual and semantic judgments. Using visibility and intuitiveness ratings collected from Korean and Texas-based U....

Metabolic health, obesity, and prognosis in chronic obstructive pulmonary disease

Metabolic syndrome is a common comorbidity in chronic obstructive pulmonary disease (COPD), yet its long-term impact on survival and exacerbations remains controversial. We investigated whether metabolic health status and body mass index (BMI) influence mortality and the rate of...

Age- and sex-adjusted genomic differences between Korean and Beat AML cohorts

Genomic profiling plays a central role in risk stratification and therapeutic decision-making in acute myeloid leukemia (AML), yet the clinical implications of population-specific genomic architectures remain incompletely defined. We conducted a prospective, multicenter study of...

Predictors of Early Versus Late Atrial Tachyarrhythmia Recurrence After Cryoballoon Ablation by Atrial Fibrillation Type

ABSTRACT Introduction Patient characteristics and predictors of early (ERAT) and late (LRAT) recurrence of atrial tachyarrhythmia by atrial fibrillation (AF) type after cryoballoon ablation (CBA) remain poorly defined. Methods Using the Korean Heart Rhythm Cryoballoon Registry (1...

Aging Biology of Bone-to-Tendon Healing and the Epigenetic Clock: A Biological-Age Readout of Rotator Cuff Healing Capacity

The “unexplained failure” of rotator cuff repair is multifactorial, but its structural endpoint is anatomically consistent, i.e., the failure of the tendon-to-bone interface (enthesis) to heal. The native enthesis is a four-zone fibrocartilaginous gradient that does not regenerat...

Parking of connected automated vehicles: vehicle control, parking assignment, and multi-agent simulation

This paper introduces a comprehensive approach to optimize parking efficiency for connected and Automated vehicle (CAVs) fleets. We present a multi-vehicle parking simulator, equipped with hierarchical path planning and collision avoidance capabilities for individual CAVs. The si...

Domain-Specific Cognitive Concordance in Older Married Couples

Importance Spousal similarity in late-life cognition has been reported, but whether concordance differs across cognitive domains remains unclear. Objective To examine whether cognitive concordance among older married couples is domain specific by comparing real couples with demog...

Impact of Concomitant Grade I Degenerative Spondylolisthesis on Clinical and Radiographic Outcomes Following Biportal Endoscopic versus Microscopic Laminectomy for Lumbar Spinal Stenosis: A Post Hoc Analysis of a Multicenter Randomized Clinical Trial

Study DesignPost hoc analysis.ObjectiveTo determine whether Meyerding grade I degenerative spondylolisthesis (DS1) modifies 12-month clinical or radiographic outcomes after biportal endoscopic laminectomy (BE-L) versus microscopic laminectomy (M-L) for lumbar spinal stenosis, and...

Evaluating Immunotherapy Outcomes in Elderly Patients with Extensive-Stage Small-Cell Lung Cancer (KCSG LU23-15)

PurposeChemoimmunotherapy has improved outcomes in extensive-stage small-cell lung cancer (ES-SCLC), but its benefit in older adults remains uncertain because this population is underrepresented in clinical trials.We evaluated the real-world efficacy of first-line atezolizumab pl...

Early On-Treatment Host Fitness Dynamics Refine Prognostic Stratification in Advanced NSCLC Receiving First-Line Immunotherapy

PurposeWe assessed whether baseline and early on-treatment measurements of host fitness using the Prognostic Nutritional Index (PNI) provide complementary prognostic information in advanced non-small cell lung cancer (NSCLC). Materials and MethodsWithin the prospective, multicent...

Blood viscosity is associated with smoking status rather than the presence of chronic obstructive pulmonary disease: findings from the Korea COPD Subgroup Study (KOCOSS)

Abstract Background The relationship between smoking and blood viscosity is well established. However, the role of blood viscosity in the development of chronic obstructive pulmonary disease (COPD) and its impact on lung function decline remains unclear. Therefore, we aimed to in...

Integrative Genomic Analysis Reveals Molecular and Clinical Disparities between Bladder and Upper Tract Urothelial Carcinoma in K-MASTER Program

Purpose: The clinical outcome of urothelial carcinoma presents significant variability, reflecting its molecular composition, epidemiologic attributes, and primary site of origin. Despite histological similarities, upper tract urothelial carcinoma (UTUC) and bladder urothelial ca...

Absolute knee extensor strength, not limb symmetry, predicts outcomes and defines a rehabilitation threshold after medial opening‐wedge high tibial osteotomy

Abstract Purpose To identify a clinically relevant body mass‐normalised knee extensor strength threshold after high tibial osteotomy (HTO) and examine how absolute strength and limb symmetry index (LSI) relate to patient‐reported outcomes (PROMs), dynamic balance and longitudinal...

Pharmacologic Treatment Response in Panic Disorder with Comorbid Medical Conditions: A Systematic and Narrative Review

Panic disorder frequently co-occurs with medical conditions, complicating diagnosis and treatment.Although pharmacotherapy is a first-line treatment for panic disorder, pharmacotherapeutic evidence for patients with medical comorbidities is limited.Therefore, this review systemat...