Kōchi University

Quality of life in hyperkalemia: baseline analysis of a cohort study of management of hyperkalemia in patients with chronic kidney disease or heart failure in Japan

Abstract Background Hyperkalemia is common in chronic kidney disease (CKD) and chronic heart failure (CHF), often leading to treatment dilemmas regarding renin–angiotensin–aldosterone system (RAAS) inhibitors. Although potassium binders and dietary restrictions are central to chr...

Cesarean delivery and overweight at 6 years of age: a prospective cohort analysis of the Japan Environment and Children’s Study

Abstract Cesarean delivery (CD) has been suggested as a potential risk factor for childhood overweight and obesity; however, evidence beyond early childhood remains inconsistent. We examined the association between CD and childhood overweight at age 6 years and explored early lif...

IL-15 drives antigen-independent increase in granzyme K+B+ CD8 T cells enriched in rheumatoid arthritis joints

OBJECTIVES: CD8 T cells co-expressing granzymes K and B (GzmK + B+) are enriched in the joint compared with peripheral blood and have been implicated in the pathogenesis of rheumatoid arthritis (RA). However, it remains unclear whether the enrichment of GzmK+B+ subsets is specifi...

Consumer preferences for domestically produced ingredients in Japan’s ready-to-eat meals and dining out: a best–worst scaling analysis

Abstract As ready-to-eat (RTE) meals and dining out become increasingly popular, limited empirical evidence exists on how domestically produced ingredients are positioned relative to other food values in these contexts. Using online survey data from Japanese consumers collected i...

Preoperative prognostic stratification of high-risk resectable pancreatic cancer: combined Podxl/itgb1 expression in EUS-FNAB specimens as a prognostic biomarker

Neoadjuvant chemotherapy with gemcitabine and S-1 (NAC-GS) is a conditionally recommended treatment for resectable pancreatic ductal adenocarcinoma (PDAC) in Japan. However, therapeutic efficacy remains limited in a subset of patients who lose surgical opportunities due to tumor...

Gold-granulite association in Precambrian terranes: A metallogenic conundrum

Gold mineralization in Precambrian high-grade metamorphic terranes, particularly those hosted within middle- to lower-crustal upper amphibolite- to granulite-facies domains, remains a metallogenic paradox. While the vast majority of economic gold resources are concentrated in epi...

Complete genome sequence of Helicobacter pylori strain NY43 harboring bacteriophage KHP30

ABSTRACT The Helicobacter pylori NY43 strain spontaneously releases the bacteriophage (phage) KHP30. Here, we report the complete genome sequence of H. pylori NY43. In addition to the chromosome of H. pylori NY43, we successfully obtained the complete sequence of the episomal pro...

Spontaneous regression of pharyngeal indeterminate dendritic cell tumor with KRAS and TP53 mutations

Indeterminate dendritic cell tumor (IDCT) is an extremely rare disease within the class of histiocytic and dendritic neoplasms [1,2]. The tumor cells are presumably derived from precursor dendritic...

The equalities of interleaving distances and cohomology interleavings of spaces over $$BS^1$$

Abstract The cohomology interleaving distance (CohID) is defined and considered in the category of persistent differential graded modules over a field. As a consequence, we show that, in the category, the distance coincides with the homotopy commutative interleaving distance , th...

Management and Outcomes of Cardiac Sarcoidosis: Insights From the Nationwide MYSTICS Registry

BACKGROUND: Cardiac sarcoidosis (CS) may lead to serious outcomes, but large-scale data are lacking because of its rarity, diagnostic uncertainty, and heterogeneous clinical presentations. Actual management and outcomes, including recurrence, are not well understood. This study a...

Fusarium oxysporum f. sp. crypti , a novel forma specialis causing Fusarium wilt of mitsuba, Cryptotaenia japonica

Fusarium oxysporum isolates causing Fusarium wilt in mitsuba (Cryptotaenia japonica Hassk.; also referred to as Japanese honeywort, Japanese honewort, or Japanese parsley) have traditionally been classified as f. sp. apii. However, some reports have indicated that the host-pathog...

Multiancestry genome-wide association and multiomics analyses elucidate spatiocellular features of multiple sclerosis genetics

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system characterized by demyelination disseminated in space and time. Here we performed a genome-wide association study (GWAS) using 688 MS cases and 205,199 controls from the Japanese population and...

Immediate Changes in Perceived Person-Centered Care and Technological Competency Following a One-Day Collective Training Program Among Mongolian Nurse Managers and Nurses Nominated for Managerial Roles: A Pilot Pre–Post Study

Background/Objectives: Person-centered care (PCC) and the Technological Competency as Caring in Nursing (TCCN) theory are increasingly emphasized in nursing leadership, but no published study has evaluated a PCC/TCCN training program among Mongolian nurse managers. This uncontrol...

From educational seminars to interpersonal diffusion: knowledge fidelity in word-of-mouth transmission of HPV vaccine information in Japan—a real-world implementation study

Abstract Background In vaccine-hesitant environments, evidence-based health information often spreads through interpersonal word-of-mouth communication within community networks. However, little empirical evidence exists regarding whether health knowledge remains accurate as it i...

Practical Comparison of a Newly Developed Software-Based Visual Acuity Test and Photoscreening in Japanese Preschool Children

Background: Early detection of vision problems in young children is crucial, as they may lead to lifelong disabilities such as amblyopia and strabismus. However, conducting visual acuity (VA) evaluations in this age group is challenging. We developed novel VA testing software tai...

Are dispersed rice planting dates linked to higher provincial yields? Evidence from Northeast Thailand

Abstract Planting date is an important determinant of wet-season rice performance in monsoon Asia. However, it is influenced not only by rainfall but also by irrigation access, drainage conditions, and field operability. This study quantified how the spatial distribution and disp...

Line-shaped Mesoscale Convective Systems in Northern Japan: Climatology and Predictive Diagnostics

Abstract This study presented a statistical analysis of line-shaped mesoscale convective systems (LS-MCSs, called “Senjo-Kousuitai”, Kato 2020) in northern Japan using a 64-year high-resolution reanalysis dataset. A significant increase in LS-MCSs frequency and rainfall intensity...

Direct speciation of ultra-trace platinum in marine ferromanganese oxides by wavelength-dispersive XAFS

Abstract Ultra-trace platinum (Pt) in marine ferromanganese oxides (FMOs) has remained inaccessible to direct XAFS analysis because of its extremely low abundance and severe interferences from co-existing elements. We achieved the first direct speciation of Pt at the 1 μg g−1 lev...

P1.214. The Effect of Combined General Anesthesia and Epidural Analgesia on Postoperative Pulmonary Complications in Thoracoscopic Esophagectomy

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – early outcomes and complications Background Although combined general anesthesia and epidural analgesia are used in open surgery to promote rehabilitation and expectoration, as well as to prevent postoper...

Porphyry Cu–Au and Cu–Mo Systems as Sources for Critical Metal Resources: A Review and Future Projection

Porphyry systems are considered as low-grade, but high-tonnage, sources of scarce critical metals such as Cu and Mo, but they also host economic by-products of precious metals such as Au and Ag as well as rare trace critical metals such as Se, In, Te, and Re. The latter are of in...