Kochi Medical School Hospital

Quality of life in hyperkalemia: baseline analysis of a cohort study of management of hyperkalemia in patients with chronic kidney disease or heart failure in Japan

Abstract Background Hyperkalemia is common in chronic kidney disease (CKD) and chronic heart failure (CHF), often leading to treatment dilemmas regarding renin–angiotensin–aldosterone system (RAAS) inhibitors. Although potassium binders and dietary restrictions are central to chr...

IL-15 drives antigen-independent increase in granzyme K+B+ CD8 T cells enriched in rheumatoid arthritis joints

OBJECTIVES: CD8 T cells co-expressing granzymes K and B (GzmK + B+) are enriched in the joint compared with peripheral blood and have been implicated in the pathogenesis of rheumatoid arthritis (RA). However, it remains unclear whether the enrichment of GzmK+B+ subsets is specifi...

Preoperative prognostic stratification of high-risk resectable pancreatic cancer: combined Podxl/itgb1 expression in EUS-FNAB specimens as a prognostic biomarker

Neoadjuvant chemotherapy with gemcitabine and S-1 (NAC-GS) is a conditionally recommended treatment for resectable pancreatic ductal adenocarcinoma (PDAC) in Japan. However, therapeutic efficacy remains limited in a subset of patients who lose surgical opportunities due to tumor...

Management and Outcomes of Cardiac Sarcoidosis: Insights From the Nationwide MYSTICS Registry

BACKGROUND: Cardiac sarcoidosis (CS) may lead to serious outcomes, but large-scale data are lacking because of its rarity, diagnostic uncertainty, and heterogeneous clinical presentations. Actual management and outcomes, including recurrence, are not well understood. This study a...

P1.214. The Effect of Combined General Anesthesia and Epidural Analgesia on Postoperative Pulmonary Complications in Thoracoscopic Esophagectomy

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – early outcomes and complications Background Although combined general anesthesia and epidural analgesia are used in open surgery to promote rehabilitation and expectoration, as well as to prevent postoper...