Kobe University Hospital

Intravitreal Onchocerca sp. With Concomitant Cerebral MRI Lesion: A Case Report.

BACKGROUND Onchocerca lupi is a zoonotic filarial nematode that primarily infects canids. Human infection is rare and typically involves the eye or subcutaneous tissue. O. lupi infection should be considered in cases of unresolved uveitis or neurological symptoms. We report a dia...

Whole exome sequencing and transcript analysis of a PTEN splice-site variant in a child with PTEN hamartoma tumor syndrome: a case report

Introduction PTEN hamartoma tumor syndrome (PHTS) is a hereditary tumor syndrome characterized by macrocephaly, neurodevelopmental disorders, mucocutaneous lesions, and predisposition to tumors. In childhood, the characteristic mucocutaneous and tumor-related manifestations may n...

Institutional enrollment volume and clinical outcomes after surgery or chemoradiotherapy for clinical stage I esophageal squamous cell carcinoma: a supplementary analysis of JCOG0502

Abstract Background Surgery and chemoradiotherapy (CRT) are standard options for clinical stage I esophageal squamous cell carcinoma (ESCC). JCOG0502, a multicenter, non-randomized, parallel-group comparison, demonstrated the non-inferiority of definitive CRT compared with surger...

Association Between PS-OCT Derived Polarimetric Entropy and RPE Cellular Metrics Measured With Adaptive Optics Imaging in Retinitis Pigmentosa

Purpose: The purpose of this study was to investigate the association between entropy values derived from the retinal pigment epithelium (RPE) layer using polarization-sensitive optical coherence tomography (PS-OCT) and RPE cellular metrics obtained by adaptive optics transsclera...