Klinikum Braunschweig

Unsteady Loss Assessment of a Transonic Compressor Stage Midspan Section

Abstract In transonic turbomachinery compressors, the aerodynamic loading is significantly increased, giving rise to complex flow phenomena, including shock boundary layer interactions. These interactions induce substantial unsteadiness and elevate loss levels that RANS models of...

DECIDER-2: Prospective randomized multicenter phase III trial of decitabine and venetoclax administered in combination with all-trans retinoic acid or placebo in patients with acute myeloid leukemia who are ineligible for induction chemotherapy

Abstract Background Acute myeloid leukemia (AML) is predominantly a disease of older patients with a poor long-term survival. Approval of the combination of venetoclax (VEN) with azacitidine (AZA) or decitabine (DAC) in the European Union in 2021 for the treatment of patients wit...