King Fahad Specialist Hospital

Programming of deep brain stimulation of the centromedian nucleus of the thalamus for drug‐resistant epilepsy: A meta‐analysis and proposed programming framework

Abstract Objective Although the centromedian nucleus of the thalamus (CM) is an increasingly considered deep brain stimulation (DBS) target for drug‐resistant epilepsy (DRE), there is significant variability in programming practices, which may contribute to heterogenous outcomes....

Public Awareness of Genetic Diseases, Preventive Screening, and Genetic Healthcare Services in the Qassim Region, Saudi Arabia: A Cross-Sectional Study

Background: Genetic diseases pose a significant public health issue in Saudi Arabia, driven by relatively high prevalence and factors such as consanguineous marriage. Increasing public awareness and understanding are crucial to improving prevention, early detection, and the use o...

EUS-guided and US-guided percutaneous splenic biopsy: a systematic review and meta-analysis of separately pooled diagnostic and safety outcomes

Ultrasound (US)-guided percutaneous splenic biopsy has been widely used to evaluate focal or diffuse splenic lesions and has shown promising efficacy and safety. Endoscopic ultrasound (EUS)-guided biopsy has emerged as an alternative approach for tissue acquisition from splenic l...

In Silico Screening of Cannabis sativa Phytochemicals as Potential Ornithine Decarboxylase Inhibitors for Anti-Leishmanial Drug-Prioritized Compound Development

Leishmaniasis remains a major neglected tropical disease with limited therapeutic options, increasing drug resistance, and significant treatment-associated toxicity. Ornithine decarboxylase (ODC), which plays an essential role in polyamine synthesis and survival of parasites, is...