King Chulalongkorn Memorial Hospital

Comparison of clinical outcomes, cost, and patient perceptions between delayed and immediate sequential bilateral cataract surgery in Thailand: a retrospective case–control study

To compare clinical outcomes, complication rates, costs, and patient perceptions—encompassing satisfaction, anxiety, pain, and visual function—between delayed sequential bilateral cataract surgery (DSBCS) and immediately sequential bilateral cataract surgery (ISBCS) in Thailand....

Screening strategies for the early detection of non-cardia gastric cancer in low- to moderate-prevalence regions: Asia-Pacific gastroesophageal cancer congress consensus 2026

Abstract Background Gastric cancer (GC) remains a major global health burden, and early detection is essential for improving patient outcomes. Although GC screening has been widely implemented in East Asian countries with a high disease burden, the optimal screening strategy for...

Cold Snare Polypectomy Versus Cold Snare Polypectomy With Submucosal Injection for 3–9 mm Colorectal Polyps: A Randomized Controlled Trial

ABSTRACT Background and Aim Incomplete resection after cold snare polypectomy (CSP) remains a concern. CSP may sometimes require a forcible pull (“forced CSP”), which increases the incomplete resection rate (IRR). Submucosal injection before CSP (SI‐CSP) may facilitate resection...

Adrenal Infections: An Underrecognized Cause of Primary Adrenal Insufficiency

INTRODUCTION: Adrenal infections are an underrecognized but clinically significant cause of primary adrenal insufficiency (PAI). OBJECTIVES: This review proposes a diagnostic algorithm for the evaluation of suspected cases. RESULTS: The most common causative pathogens are Mycobac...

Characteristics and associated risk factors of opportunistic infection in children with systemic lupus erythematosus in under-resourced areas

Objective Infection is a major factor in morbidity and mortality among pediatric systemic lupus erythematosus (SLE) patients, particularly opportunistic infections (OI), which can result in severe clinical outcomes. There is a scarcity of data regarding OI in children with SLE in...

Prenatal bisphenol A exposure is associated with sex-specific cerebellar transcriptomic alterations and altered motor performance in rat offspring

Abstract Background Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by a significant male-to-female bias and cerebellar abnormalities. Although bisphenol A (BPA) has been increasingly investigated as a potential environmental risk factor, the molecu...

Topical tissue adhesive versus subcuticular suturing in minimally invasive spine surgery a randomized paired incision trial

Abstract Skin closure technique may influence wound healing, cosmetic outcomes, and operative efficiency in minimally invasive spine surgery (MISS). This prospective assessor- and patient-blinded randomized controlled trial compared topical tissue adhesive with subcuticular sutur...

Validity and reliability testing of a Buddhist death acceptance scale among healthy Thai older persons (BDAS-O)

Death acceptance is a key component of psychological well-being in later life, influencing emotional adjustment, quality of life, and end-of-life preparedness. However, culturally appropriate and psychometrically sound instruments to assess death acceptance among older adults in...

Metagenomic Deep Sequencing Identifies Gene Mutations Associated with Chemotherapeutic Resistance in Vitreoretinal Lymphoma

Purpose To identify gene mutations associated with chemotherapeutic resistance in patients with vitreoretinal lymphoma (VRL) using metagenomic deep sequencing (MDS) of intraocular specimens.Methods Patients with VRL confirmed by cytopathology and immunohistochemistry, flow cytome...

Prenatal BPA exposure is associated with a sex-stratified TF–RBP–Ccar1 splicing regulatory network, purkinje cell layer alterations, and transcriptomic concordance with PTEN I135L cerebellar organoid models

Autism spectrum disorder (ASD) is a pervasive neurodevelopmental condition characterized by social communication deficits and restricted, repetitive behaviors, exhibiting a consistent male bias in prevalence. Emerging evidence suggests that prenatal exposure to bisphenol A (BPA),...

Global in vitro antimicrobial susceptibility profiles of Mycobacterium abscessus: a systematic review and meta-analysis

Mycobacterium abscessus (MAB) exhibits extensive antimicrobial resistance, contributing to major treatment challenges and frequent therapeutic failure. This systematic review and meta-analysis aimed to assess the global in vitro susceptibility of antimicrobial agents against clin...

Asian Neurogastroenterology and Motility Association and Asia-Pacific Association of Gastroenterology Chronic Constipation Consensus 2026.

Background/Aims: : Chronic constipation is a common gastrointestinal (GI) disorder in Asia, characterized by heterogeneous symptom presentation, frequent overlap with other GI symptoms, and limited access to specialized diagnostic tests in many settings. These factors contribute...

Associations of ambient temperature and PM2.5 concentration with temporal variability in emergency department visits for acute gastrointestinal illnesses in central Bangkok, Thailand: a 5-year retrospective analysis

The combined effects of temperature and air pollution on acute gastrointestinal (GI) illnesses remain underexplored in tropical settings. This study examined the association between ambient temperature, fine particulate matter (PM2.5), and emergency department (ED) visits for gas...

Smart Lithotripsy: Lasers, Energy Sources and Efficiency

PURPOSE OF REVIEW: To examine the evidence on contemporary lasers and provide a practical framework for platform selection, parameter optimization, and thermal safety based on the principles of smart lithotripsy. RECENT FINDINGS: Holmium: yttrium-aluminum-garnet (Ho:YAG) remains...

Single-cell morphological responses as predictors of ciprofloxacin resistance in Acinetobacter baumannii

ABSTRACT The rise of antimicrobial resistance (AMR) coincides with a declining pipeline of new antibiotics, underscoring the urgent need for rapid and accurate antibiotic susceptibility testing (AST). Single-cell AST approaches offer the potential to shorten diagnostic turnaround...

Percutaneous transvenous mitral commissurotomy during pregnancy: a contemporary Southeast Asian experience

Abstract Background Severe rheumatic mitral stenosis during pregnancy is associated with substantial maternal and fetal morbidity because physiological hemodynamic changes may precipitate heart failure and pulmonary hypertension. Percutaneous transvenous mitral commissurotomy (PT...

Emerald effluent in severe pancreatitis: Acute PD as dual-action support?

A 50-year-old man with severe presumed gallstone pancreatitis, multiorgan failure, and oliguric stage 3 acute kidney injury underwent bedside acute peritoneal dialysis (PD) for haemodynamically tolerated kidney support and intra peritoneal lavage. Catheter insertion drained a lar...

Laboratory Concordance and Prognostic Impact of 10‐Color Flow Cytometry and Next‐Generation Sequencing‐Based Immunoglobulin Gene Assay for Measurable Residual Disease Monitoring in Adult B‐Cell Acute Lymphoblastic Leukemia: A Multicenter Study From Thai Acute Leukemia Working Group ( TALWG )

ABSTRACT Aims Measurable residual disease (MRD) is a key prognostic marker for patient survival. This study evaluated concordance between 10‐color flow cytometry and next‐generation sequencing (NGS)–based immunoglobulin heavy chain (IGH) gene assays for MRD detection and to asses...

Assessment of left atrial native T1 values using non-contrast 3.0 T cardiac magnetic resonance imaging: a feasibility and reproducibility study

Atrial cardiomyopathy (ATC) is characterized by structural and functional atrial remodeling and is associated with adverse cardiovascular outcomes. Native T1 mapping has emerged as a sensitive technique for tissue characterization; however, data on left atrial (LA) native T1 mapp...

Landscape of industry-sponsored oncology trials across the Thai Society of Clinical Oncology (TSCO): a 12-year multicenter analysis

Cancer remains a major global health challenge and is a leading cause of morbidity and mortality in Thailand. Industry-sponsored oncology trials (ISOTs) provide critical access to innovative therapies, including targeted agents, immunotherapies (IO), and antibody–drug conjugates...