King Abdullah Medical City

Gas-driven needle-free dental injection enables tunable and predictable soft-tissue penetration: high-speed kinematic and micro-computed tomography validation

Needle-free jet injectors are a promising alternative to conventional dental needles, particularly for patients with injection-related fear. However, the actuation mechanism can substantially affect jet formation, delivery consistency, and tissue penetration. This study compared...

Beclin-1 and HIF-1α immunohistochemical expression in breast carcinoma: insights into tumor biology

Breast carcinoma is a biologically heterogeneous disease in which tumor behavior and clinical outcome are influenced by multiple cellular pathways, including autophagy and hypoxia. Beclin-1, a key autophagy-related protein, and hypoxia-inducible factor-1α (HIF-1α), a central regu...