Kinderkrankenhaus auf der Bult

Subclinical cardiac involvement during diabetic ketoacidosis at type 1 diabetes onset in youth: biomarker elevation, altered diastolic filling, and reduced global longitudinal strain: a prospective cohort study

Abstract Background Diabetic ketoacidosis (DKA) may be associated with cardiac involvement. Increased cardiac biomarkers and abnormalities in cardiac function were mainly reported in adults with type 1 diabetes (T1D). Pediatric data are lacking. This study therefore assessed card...

LDL hypercholesterolemia in children: genetic influence and response to lifestyle advice - follow-up of the Fr1dolin-trial

BACKGROUND AND AIMS: Although familial hypercholesterolemia (FH) is common and associated with significant cardiovascular morbidity, screening programs are scarce. Furthermore, the effectiveness of nutritional advice for parents on children's LDL cholesterol (LDL-C) levels is unc...

The economic impact of pediatric RSV-related lower respiratory tract infection in Germany: evidence from the PAPI study

BACKGROUND: Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infections (LRTI) in infants and young children. While considerable research has described the clinical burden and direct medical costs of RSV in Germany, the broader economic impact...