Kindai University Sakai Hospital

Smartphone-measured heart rate variability and quality of life in patients with gynecological cancer: a multicenter prospective study

In this study, we aimed to investigate the association between heart rate variability (HRV) and quality of life (QoL) in patients with gynecological cancer and examine whether continuous HRV monitoring may help identify QoL deterioration. This multicenter, prospective, observatio...

Two stress-responsive kinases suppress ferroptosis by activating antioxidant programs under mild oxidative stress

Cancer cells maintain chronically elevated levels of reactive oxygen species (ROS) while relying on robust antioxidant programs to preserve redox homeostasis and viability. Although therapeutic strategies that disrupt this balance to induce lethal oxidative stress and ferroptosis...

[ 18 F ] PSMA ‐1007 PET –Based Recurrence Site Distribution and Predictors of Metastatic Disease in Patients With Biochemical Recurrence of Prostate Cancer

ABSTRACT Objectives Prostate‐specific membrane antigen positron emission tomography (PSMA‐PET) is a sensitive imaging modality for detecting recurrent prostate cancer following definitive local therapy. However, evidence on 18 F‐labeled PSMA tracers in Japanese patients with bioc...