Kindai University Hospital

Impact of baseline renal function on the clinical outcomes and safety of adjuvant nivolumab in high-risk urothelial carcinoma: a multicenter retrospective real-world study

Abstract Background Adjuvant nivolumab prolongs disease-free survival (DFS) in patients with urothelial carcinoma (UC) after radical surgery; however, evidence in those with reduced baseline renal function is limited. We investigated the impact of baseline creatinine clearance (C...

Intraprocedural Tail-First Pulmonary Artery Migration of a Leadless Pacemaker: A Protective Sleeve–Assisted Helix-Side Retrieval Strategy: a case report

Abstract Background Leadless pacemaker migration into the pulmonary artery is an exceptionally rare but potentially serious complication. Tail-first (proximal helix–oriented) migration poses additional risk, as traction on the exposed helix may cause vascular injury. Case summary...

Clinical Impact of Gleason Pattern 5 on Doublet Versus Triplet Therapy in Metastatic Hormone‐Sensitive Prostate Cancer

BACKGROUND: Upfront treatment intensification with androgen deprivation therapy (ADT) plus an androgen receptor pathway inhibitor has become a standard approach for metastatic hormone-sensitive prostate cancer (mHSPC). However, prognosis remains poor for some patients despite sec...