Kharkiv National Medical University

Efficacy and Safety of Sacituzumab Govitecan for Breast Cancer

Objectives: Sacituzumab govitecan (SG), a Trop-2-directed antibody-drug conjugate, has demonstrated clinical activity in HER2-negative breast cancer. Our meta-analysis aimed to evaluate the efficacy and safety of SG compared with standard chemotherapy in patients with breast canc...

Molecular epidemiology and management of non-tuberculous mycobacteria isolated from patients in Ukraine, 2022–2024

Non-tuberculous mycobacteria (NTM) are increasingly recognized worldwide as significant causes of chronic pulmonary disease, particularly among individuals with underlying structural lung disorders or immunosuppression. However, data on the epidemiology and clinical management of...

Perioperative outcomes and predictors of mortality after pericardiectomy for constrictive pericarditis in Africa: a systematic review and meta-analysis

Abstract Background Constrictive pericarditis remains a significant cause of heart failure in Africa, predominantly due to tuberculosis; however, pericardiectomy outcomes across African settings have not been systematically synthesised. This review aimed to determine the pooled p...