Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences

Synthesis and biological characterization of formononetin derivatives against phytopathogenic oomycete and bacteria: preliminary mechanisms, theoretical predictions, and biosafety evaluation

Abstract Background The increasing prevalence of phytopathogenic oomycetes and bacteria, particularly Phytophthora capsici ( Pc ) and Xanthomonas oryzae pv. oryzae ( Xoo ), poses severe threats to global agricultural production. Developing novel antimicrobial agents with dual ant...

A telomere-to-telomere reference genome for Rosa roxburghii reveals lineage-specific diversification of triterpenoid biosynthesis

Abstract Rosa roxburghii ( RRT ) is a nutritionally and medicinally important Rosaceae species that accumulates diverse bioactive compounds, making it an excellent system for investigating the genetic basis and evolutionary diversification of specialized metabolism. Here, we repo...