Institution
Keck Hospital of USC
Recent research
- BiologyOpen access
Abstract DNA damage from routine cellular processes or exogenous insults can have a lasting impact on gene regulation beyond genetic mutations. The prevailing paradigm for the consequences of DNA damage repair revolves around restoration of the original genetic sequence, but long...
- Biology
Sexual dimorphisms in mechanisms of pressure natriuresis
Aim: The renal pressure-natriuresis response defines the blood pressure set point and maintains circulating volume. In male rats, the mechanisms involve trafficking and inactivation of renal proximal sodium transporters. Mechanisms may differ in females due to sex differences in...
- Health & Medicine
Background: Total wrist arthroplasty (TWA) is a motion-preserving alternative to wrist fusion for end-stage wrist arthritis, but concerns regarding long-term durability continue to limit broader use. Reported 10-year survivorship ranges from 70% to 80%, although real-world failur...
- BiologyOpen access
Breakdown of the blood–retinal barrier (BRB) is implicated in many blinding retinal diseases, including diabetic macular edema, neovascular age-related macular degeneration, and retinal vein occlusion. Anti-vascular endothelial growth factor (anti-VEGF) therapies or laser photoco...
- Health & MedicineOpen access
PurposeThe purpose of this study was to explore the experiences of parents of youth and young adults with intellectual and developmental disabilities who have undergone the transition from pediatric to adult healthcare as well as community-based transition and adult-focused servi...
- Health & Medicine
Top 10 Tips Palliative Care Clinicians Should Know About Preventing Burnout
Health care worker burnout is a potential job hazard. Palliative care clinicians (PCCs) are especially vulnerable due to the intense emotional and challenging demands of the work. Creating environments for PCCs to thrive is the responsibility of the organization, however, PCCs ha...