Kateb University

Palpitations in children and adolescents in the emergency department: a state-of-the-art narrative review of arrhythmia risk, diagnostic strategy, and disposition

BACKGROUND: Palpitations are not an uncommon complaint in the paediatric emergency department, causing significant anxiety for families concerned about serious heart disease. However, most cases are benign, often stemming from normal physiological responses like fever or anxiety....

Recent advances in universal influenza vaccine platforms: paving the way for universal H5N1 vaccines and pandemic readiness

Abstract The H5N1 influenza threat is a significant issue to the overall health of the population in the world, and it demands new approaches in vaccine development and implementation. The critical path forward is the development of universal vaccine platforms, which provide long...

Efficacy and safety of oncolytic herpes simplex virus therapy in solid tumors: a systematic review and meta-analysis of 38 clinical trials

Abstract Background Oncolytic herpes simplex virus (oHSV) therapy represents a novel immunotherapeutic approach for solid tumors. Despite regulatory approval of talimogene laherparepvec (T-VEC) for advanced melanoma, comprehensive pooled estimates of efficacy and safety across di...

Efficacy of early blood purification on serum inflammatory mediators in severe acute pancreatitis: a systematic review and meta-analysis

Severe acute pancreatitis (SAP) is the most critical form of acute pancreatitis (AP), characterized by a dysregulated systemic inflammatory response that drives early organ failure and mortality. Current management remains mainly supportive. Early blood purification (EBP) has bee...