Kaohsiung Veterans General Hospital

Value perceptions and implementation priorities for public PHR adoption in Taiwan: an importance–performance analysis with the Chuchiming Index

Abstract Background Value perceptions of personal health record (PHR) components at the pre-adoption stage remain underexplored, despite their critical role in promoting the adoption of public PHRs. Importance–Performance Analysis (IPA) may have limitations in identifying priorit...

¹⁸F-sodium fluoride PET/CT as a complementary measure of osteoblastic disease burden in axial spondyloarthritis: a prospective exploratory study

PURPOSE: To determine whether SIJ ¹⁸F-NaF uptake is associated with MRI-defined inflammation and structural damage and whether it provides a complementary measure of osteoblastic disease burden. METHODS: In this prospective exploratory study, 43 adults with chronic low back pain...

Targeting tryptophan hydroxylase 1 restricts growth and suppresses plasticity in neuroendocrine prostate cancer

Advanced prostate cancer has increasingly developed a lethal neuroendocrine form, small cell/neuroendocrine prostate cancer (NEPC), as a consequence of the widespread use of highly potent androgen receptor signaling inhibitors in castration-resistant disease. The molecular mechan...

Reproducibility-driven clinical translation of spatial multi-omics in precision medicine

Spatial multi-omics has emerged as a transformative approach for decoding tissue architecture by simultaneously profiling transcriptomic, proteomic, and epigenomic layers within their histological context. Yet despite rapid technological diversification, the transition from explo...

Prognostic Relevance and Immune Correlates of DAPK1 Expression and CD4+/CD8+ T-Cell Infiltration in Oral Squamous Cell Carcinoma

Background: Death-associated protein kinase 1 (DAPK1) is a key regulator of apoptosis and immune responses; however, its prognostic significance in oral cancer remains insufficiently characterized. This study investigated the prognostic relevance of DAPK1 in oral squamous cell ca...

The efficacy and safety of monthly intravenous methylprednisolone pulse therapy in Taiwanese alopecia areata patients: A retrospective cohort study

Abstract Background: Intravenous methylprednisolone pulse (IVMP) therapy has been widely used for treating severe or recalcitrant alopecia areata (AA), but treatment protocols and efficacy vary. Objectives: This study aims to evaluate the efficacy of IVMP, identify predictive fac...