Kangwon National University Hospital

Lipid Burden and Efficacy of Preventive PCI of Vulnerable Atherosclerotic Coronary Plaques: Post Hoc Analysis From the PREVENT Trial

BACKGROUND: Preventive percutaneous coronary intervention (PCI) of non–flow-limiting lesions (fractional flow reserve >0.80) that are high-risk plaques has emerged as a potential strategy to reduce cardiac events. However, identifying which lesions derive the greatest benefit fro...

Preoperative intravenous iron and red blood cell transfusion requirements in elderly intertrochanteric femoral fractures

Abstract Background Intravenous (IV) iron is used in patient blood management for elderly patients with hip fractures, but its effectiveness in reducing red blood cell (RBC) transfusion remains unclear. This study evaluated the effect of preoperative IV iron on perioperative RBC...

Contrasting Prognostic Value of Discordance Between Resting Distal-to-Aortic Coronary Pressure Ratio and Fractional Flow Reserve in Coronary Artery Disease

BACKGROUND: Discordance between nonhyperemic pressure ratios and fractional flow reserve (FFR), observed in up to 20% of cases, complicates clinical decision-making for coronary revascularization and warrants further investigation of its clinical implications. This study aimed to...

Artificial Intelligence for Endoscopic Diagnosis of Gastric Premalignant Lesions

Gastric cancer is a leading cause of cancer-related mortality worldwide. The Correa cascade posits that intestinal-type gastric adenocarcinoma develops through a stepwise progression from chronic gastritis to atrophic gastritis, intestinal metaplasia, and dysplasia, highlighting...

Application of Fibronectin-Coated Microparticles for Isolation of Human iPSC-Derived MSCs

Abstract BACKGROUND : Bone marrow–derived MSCs (BMMSCs) are limited by availability, donor variability, and age-related decline, highlighting the need for alternative MSC sources. Induced pluripotent stem cells (iPSCs) offer a scalable solution. This study introduces a novel thre...

Fibroblast Growth Factor Signaling in Lung Diseases: From Biological Roles to Therapeutic Delivery Strategies

As human longevity continues to increase globally, the prevalence of age-related deterioration and associated chronic lung diseases has risen in parallel. Unlike many organs, the lung is continuously exposed to environmental insults, leading to cumulative cellular damage, impaire...

Retinal disease classification from spectral domain optical coherence tomography using lesion attentive fusion

Retinal diseases such as central serous chorioretinopathy (CSC) and neovascular age-related macular degeneration (nAMD) can cause permanent vision loss, and their diagnosis from three-dimensional spectral-domain optical coherence tomography (SD-OCT) volumes is challenging because...