Kandahar University

Understanding the Mortality Trends in Patients With Ventricular Arrhythmias and Cardiomyopathy: A 25‐Year Retrospective Analysis From 1999–2024

BACKGROUND: Ventricular Arrhythmias (VA) associated with Cardiomyopathy (CM) continues to be the major cause of death. However, a national longitudinal study examining mortality trends from these conditions is still lacking. This study assessed mortality trends due to these condi...

Immune checkpoint inhibitors for African people living with HIV: T-cell exhaustion, endemic co-infections, and the oncology trial gap

Immune checkpoint inhibitors (ICIs) have fundamentally transformed modern oncology by unleashing the body’s anti-tumor immunity, yet people living with HIV (PLWH) were systematically excluded from the pivotal registration trials. This evidence gap is especially consequential in s...

Anaplastic thyroid carcinoma with postpartum progression to stage IVC disease in a 23-year-old pregnant woman: a rare presentation with diagnostic challenges and treatment barriers leading to poor disease control and fatal outcome—a case report

Abstract Background Anaplastic thyroid carcinoma is a rare and aggressive malignancy, with a poor prognosis and is infrequently encountered in young individuals, particularly pregnant women. This case highlights the diagnostic and therapeutic challenges posed by this aggressive c...

Predictive modeling of oral squamous cell carcinoma risk using a multi-parametric machine learning framework integrating clinical, sociodemographic, and salivary biomarker data

Abstract Oral Squamous Cell Carcinoma (OSCC) represents a major public health challenge due to diagnostic delays and the invasive nature of conventional biopsy techniques, underscoring the need for accurate, non-invasive prognostic tools. This study develops and validates a multi...

Satisfaction of antenatal care services and its associated factors among pregnant women in selected public health facilities in Kandahar, Afghanistan

Research indicates that satisfaction with antenatal care (ANC) services remains suboptimal across several low-and middle-income countries (LMICs). However, there is a research gap on the satisfaction of ANC services in Afghanistan. Therefore, this study aims to assess satisfactio...

Adequate tetanus toxoid immunization and its correlates among married women with a recent live birth in Afghanistan: Insights from a national survey

This study aimed to determine the prevalence and correlates of adequate tetanus toxoid (TT) immunization among married women in Afghanistan. This cross-sectional study analyzed data from the 2022-2023 Afghanistan Multiple Indicator Cluster Survey (MICS), focusing on 12,450 marrie...

Efficacy of rituximab plus lenalidomide regimens in follicular lymphoma: a meta-analysis of randomized controlled trials

Follicular lymphoma (FL) is an incurable, indolent non-Hodgkin lymphoma with a high relapse rate despite effective chemoimmunotherapy. Lenalidomide, an immunomodulatory agent, in combination with rituximab (R²), has been evaluated as an alternative to chemoimmunotherapy and to ot...

Coverage and factors associated with receipt of early newborn postnatal care components in Afghanistan: findings from the 2022–2023 multiple indicator cluster survey

BACKGROUND: Neonatal mortality remains high in low‑ and middle‑income countries, where early postnatal care (PNC) within 48 hours can avert many deaths. Yet neither the national coverage of newborn PNC nor the factors associated with its receipt have been assessed. OBJECTIVES: We...