Kaifeng University

Efficacy and Safety of Crisugabalin for Inadequately Controlled Diabetic Peripheral Neuropathic Pain: A Randomized, Active‐Controlled, Phase 2 Trial

AIMS: Crisugabalin (HSK16149), a selective γ-aminobutyric acid (GABA) analog, has shown preliminary efficacy in controlling diabetic peripheral neuropathic pain (DPNP), but efficacy in patients with inadequate response to prior pregabalin treatment remains unknown. MATERIALS AND...

Artificial intelligence use and personalized learning in higher education: pathways toward sustainable development goals and student mental health

Purpose This study aims to examine how artificial intelligence use (AIU) and personalized learning contribute to SDG-4 quality education (QE) and students’ mental health (MH) in higher education, and the study also investigates whether AIU statistically mediates the relationships...

Effectiveness and Safety of Fixed‐Dose Combination Metformin and Empagliflozin in Type 2 Diabetes: A Prospective, Multicenter, Real‐World Study From China

BACKGROUND: This study assessed the real-world effectiveness and safety of a fixed-dose combination (FDC) of metformin and empagliflozin in Chinese patients with type 2 diabetes mellitus (T2DM). METHODS: This prospective, multicenter, real-world study enrolled consecutive patient...

Comparison of long-acting versus short-acting growth hormone therapy in children with idiopathic short stature: a retrospective cohort study with advanced causal inference methods

To compare the efficacy and safety of polyethylene glycol-modified recombinant human growth hormone (PEG-rhGH) versus daily rhGH in children with idiopathic short stature (ISS) during 12–24 months of follow-up and to propose individualised treatment strategies incorporating mid-p...