John Hunter Hospital

A call for action with the burden of cirrhosis in Australia

Unlike most other chronic diseases and cancers in Australia, outcomes for cirrhosis and hepatocellular cancer are not improving. Public hospitals are overwhelmed by decompensated cirrhosis and struggling to provide best practice care for the large population of patients with less...

Sex and Mortality Among Patients with Papillary Thyroid Cancer

Importance Unlike patient age, which has been a well-established and routinely used primary biological prognostic factor in the risk stratification of papillary thyroid cancer (PTC), the prognostic value of patient sex remains controversial in this common endocrine malignant neop...

Patient-reported gestational weight gain care provided by general practitioners: a cross-sectional study

Australian clinical practice guidelines recommend all pregnant people receive routine antenatal care for gestational weight gain (GWG). All antenatal care providers (ACP) including general practitioners (GP) are recommended to assess weight and provide advice on recommended GWG,...

Same-day discharge appendicectomy protocol (SDAP): implementation and outcomes from an Australian prospective study

Acute appendicitis is one of the three most common causes for emergency admission for which many patients with uncomplicated appendicectomies require minimal post-operative care. International studies have demonstrated same-day discharge appendicectomy protocols as a safe managem...

Implementing univerSal TeleprehabiliTation into cAnceR caRe pathwayS (STTARRS Trial): protocol for a hybrid type 1 multi-centre randomised controlled trial and nested sub study

Abstract Background Postoperative complications are common after major cancer surgeries, occurring in 25–50% of patients. They delay recovery and adversely affect both cancer-free and overall survival. Intervention to optimise patients’ physical and psychological wellbeing before...

A mixed methods evaluation of pleural procedural experience and training in intensive care trainees

Abstract Background Pleural procedures are key skills for Intensive Care Unit (ICU) doctors but can be associated with serious complications. We aimed to explore ICU junior doctors’ training, experience, and confidence in performing pleural procedures. Methods The study was a pro...

Beyond the protocol: navigating ethics and governance in the multicentre implementation trials – the QASC Australasia and T3 Trials

OBJECTIVE: To describe and compare ethics and governance approval timelines for the Quality in Acute Stroke Care (QASC) Australasia Trial (2021-present) and Triage, Treatment, and Transfer of Patients with Stroke in Emergency Departments (T3) Trial (2012-2014), benchmarking again...

Fibrinogen Early In Severe Trauma studY II (FEISTY II): study protocol for a randomised clinical trial of fibrinogen concentrate vs cryoprecipitate in traumatic haemorrhage in Australia and New Zealand

Haemorrhage is a leading cause of preventable death amongst severe trauma patients and is often complicated by hypofibrinogenaemia. Fibrinogen replacement can be achieved using fibrinogen concentrate (FC) or Cryoprecipitate (Cryo), but comparative evidence in traumatic haemorrhag...