Jinnah Postgraduate Medical Center

Molecular detection and risk factors of carbapenemase -encoding gene among the Gram-negative uropathogens associated with catheter-associated urinary tract infection

Carbapenem-resistant Gram-negative bacteria frequently cause catheter-associated urinary tract infections (CA-UTIs). The objectives of this study included investigating prevalence, drug-resistance mechanisms, and risk factors associated with the infections caused by carbapenemase...

Real-world safety and effectiveness of empagliflozin (Diampa®) alone or in combination with metformin (Diampa-M®) in patients with type 2 diabetes mellitus in Pakistan: a multicenter observational study

Abstract Background Type 2 diabetes mellitus (T2DM) is a growing public health challenge in Pakistan, where poor glycemic control is common. Sodium–glucose co-transporter 2 (SGLT2) inhibitors, such as empagliflozin, have shown glycemic, cardiovascular, and renal benefits in contr...

Hepatitis E vaccination in women of childbearing age: safety and tolerability outcomes

Abstract Background and objective Hepatitis E virus is a major cause of acute viral hepatitis and is endemic in Pakistan, where it contributes substantially to morbidity and mortality among women of childbearing age. The Hecolin vaccine is a potentially useful preventive measure,...

Outcomes of Moderate-to-Severe Traumatic Brain Injury in a Low-Resource Setting

Importance: No study from a low- and middle-income country (LMIC) has reported long-term mortality and quality of life (QOL) after moderate to severe traumatic brain injury (msTBI), highlighting its burden and recovery trajectories. Objectives: To measure short- and long-term mor...