Jilin Academy of Traditional Chinese Medicine

Oxypaeoniflorin Attenuates Alcohol‐Associated Liver Disease, Potentially Involving TEAD4 ‐Mediated Inflammatory Signaling Cascades

ABSTRACT This study investigates the hepatoprotective effects and underlying molecular mechanisms of Oxypaeoniflorin (Opae) against alcohol‐associated liver disease (ALD). An in vivo ALD mouse model was established by chronic feeding of Lieber‐DeCarli EtOH‐containing liquid diets...

Estimated glucose disposal rate and incident cardiovascular disease across ageing cohorts in China, England, and the United States: cross-national consistency and transportability

The estimated glucose disposal rate (eGDR), an insulin-resistance surrogate derived from routine clinical variables, has been associated with cardiovascular disease (CVD). We examined its association with incident CVD, cross-national transportability, and incremental discriminati...