Jiangsu Vocational College of Medicine

Molecular subclassification of MGMT-unmethylated high-grade glioma identifies divergent tumor states and therapeutic vulnerabilities

MGMT-unmethylated high-grade glioma (HGG) is associated with poor response to temozolomide and limited therapeutic options. However, substantial molecular heterogeneity exists within this clinically defined subgroup and remains insufficiently characterized. Transcriptomic and cli...

The effect of epidural analgesia with hydromorphone combined with ropivacaine on intrapartum fever in women undergoing vaginal delivery

Epidural-related maternal fever (ERMF) is a well-recognised complication of epidural labor analgesia, with a significantly higher incidence compared to parturients who do not receive epidural analgesia. We hypothesised that hydromorphone combined with ropivacaine during epidural...

Crystal structure of 4,4′-bis(4-methylphenyl)-2,2′-bipyridine-κ 2 N , N ′-bis(1-phenyl-pyrazole-κ 2 C , N )-iridium(III) hexafluorophosphate —dichloromethane(1/1), C 42 H 36 Cl 2 F 6 IrN 6 P

Abstract C 42 H 36 Cl 2 F 6 IrN 6 P monoclinic, P 2 1 / n (no. 14), a = 9.4619(3) Å, b = 20.1692(5) Å, c = 21.3508(6) Å, β = 95.886(1)°, V = 4053.1(2) Å 3 , Z = 4, R gt ( F ) = 0.0384, wR ref ( F 2 ) = 0.1062, T = 150(2) K.

The Impact of Market Orientation and Patient Capital on New-Quality Productive Forces: An Empirical Study Based on the Mediating Effects of Green Technology Innovation

Based on A-share-listed manufacturing firms in China from 2012 to 2024, this paper obtains 11,626 firm-year observations after sample screening. We construct a market-orientation indicator via text mining and examine its association with new-quality productive forces, as well as...

Temporal maintenance of an adolescent suicide attempt screening score in national surveys

Screening scores may retain risk ranking while their probabilities become inaccurate in later populations. The information needed to repair this temporal drift is rarely quantified for adolescent suicide screening. We analyzed 5 independent national Youth Risk Behavior Survey cro...

A causal semantic intervention framework for few-shot SAR-ATR

Few-shot synthetic aperture radar automatic target recognition (SAR-ATR) remains challenging due to limited labelled samples. Most existing few-shot SAR-ATR methods recognize targets merely from visual features, and their recognition process is easily affected by biases introduce...

Electric vehicle charging planning in complex systems considering HARL dynamic pricing

Abstract To address the challenges of spatio-temporal coordination and economic optimization for electric vehicles (EVs) charging infrastructure planning in energy-transportation coupled networks. we propose an innovative planning framework that integrates the HARL dynamic time-o...

Sex differences in neurogenic hypertension: estrogen modulation of NADPH oxidase signaling in the rostral ventrolateral medulla

Abstract Neurogenic hypertension is characterized by sustained sympathetic activation arising from dysregulation within the central autonomic network. The rostral ventrolateral medulla (RVLM) is a major sympathetic premotor region that integrates reflex, neurohumoral, inflammator...