JiangSu Armed Police General Hospital

Associations of sedentary time and cardiovascular health with gallstone disease: evidence from a prospective cohort study

Prolonged sedentary time and poor cardiovascular health (CVH) may be associated with gallstone disease (GSD). However, prospective evidence evaluating their joint associations with incident GSD remains limited. We aimed to examine the individual and joint associations of sedentar...

Bilayer Polycaprolactone (Mitomycin C)/Poly(L-Lactic Acid)/Gelatine (Dimethyloxalylglycine) Nanofibres for Diabetic Wound Repair

Background: Diabetic skin wounds arise from chronic hyperglycaemia, peripheral neuropathy, microvascular dysfunction, and compromised immunity. Chronic ulcers are further complicated by infection and local ischaemia–hypoxia, which collectively impede tissue repair. Conventional i...

Breaking the Lipid Bottleneck: A Mitophagy‐Driven Nanoregulator Amplifies Ferroptosis for Colorectal Cancer Immunotherapy

ABSTRACT Colorectal cancer (CRC) therapy is severely constrained by the immunosuppressive tumor microenvironment (TME). This study presents a TME‐responsive nanometabolic regulator, ZnO 2 @Fe@HA (ZFH), designed to bridge mitochondrial dysfunction, lipid reprogramming, and ferropt...

Design and application of a pedicled lumbogluteal fasciocutaneous flap based on the fourth lumbar artery perforator and neurotrophic vascular network

To explore the anatomy and design of a lumbogluteal fasciocutaneous flap with a pedicle based on the fourth lumbar artery perforator and neurotrophic vascular network. Based on the anatomic findings of the lumbogluteal region in 15 human cadavers, a special lumbogluteal fasciocut...