JiangSu Armed Police General Hospital

Breaking the Lipid Bottleneck: A Mitophagy‐Driven Nanoregulator Amplifies Ferroptosis for Colorectal Cancer Immunotherapy

ABSTRACT Colorectal cancer (CRC) therapy is severely constrained by the immunosuppressive tumor microenvironment (TME). This study presents a TME‐responsive nanometabolic regulator, ZnO 2 @Fe@HA (ZFH), designed to bridge mitochondrial dysfunction, lipid reprogramming, and ferropt...

Design and application of a pedicled lumbogluteal fasciocutaneous flap based on the fourth lumbar artery perforator and neurotrophic vascular network

To explore the anatomy and design of a lumbogluteal fasciocutaneous flap with a pedicle based on the fourth lumbar artery perforator and neurotrophic vascular network. Based on the anatomic findings of the lumbogluteal region in 15 human cadavers, a special lumbogluteal fasciocut...