Jiangjin Central Hospital

Deep learning-powered virtual eosin-based elastic fiber framework imaging improves objective grading and prognostic stratification of lung adenocarcinoma

Histological grading of lung adenocarcinoma is limited by interobserver variability, particularly when distinguishing noninvasive lepidic growth from invasive patterns. This distinction depends on evaluation of the alveolar elastic fiber framework, which is often insufficiently v...

Honokiol Suppresses Glioma Cell Proliferation by Disrupting SUMO1-YAP1 Conjugation and Promoting YAP1 Proteasomal Degradation

Among primary central nervous system malignancies in adults, malignant glioma ranks first in incidence, with glioblastoma (GBM) standing as its most aggressive phenotype. This malignancy remains a devastating disease with limited therapeutic options, largely owing to the intricat...

Pregnancy loss and prevalent cardiometabolic multimorbidity: a two-stage individual participant data analysis of CHARLS, ELSA, and HRS

Cardiovascular disease remains the leading cause of death worldwide, and cardiometabolic multimorbidity (CMM) is associated with substantially higher mortality and reduced life expectancy. Pregnancy loss is common and has been linked to later cardiovascular risk, but multinationa...