Jeonbuk National University Hospital

Expanding the Clinical Spectrum of ARSACS: An Atypical Adolescent-Onset Presentation with Compound Heterozygous SACS Variants

Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a rare hereditary neurodegenerative disorder caused by biallelic pathogenic variants in SACS.Initially described in the French-Canadian population, ARSACS is now recognized worldwide and ranks among the most co...

Linguistic markers in schizophrenia patients with cognitive deficit: a machine learning study using Korean speech

Although the relationship between schizophrenia (SZ), formal thought disorder, and cognition has been extensively studied, comparatively less is known about which automatically extracted linguistic features are associated with cognitive status in SZ. We analyzed lexical, syntacti...

Optic neuropathy and ethambutol exposure in a declining tuberculosis population: a nationwide cohort study in Korea

Although global tuberculosis (TB) incidence has declined, ethambutol (EMB) remains a key component of first-line therapy and may cause potentially irreversible ethambutol-induced optic neuropathy (EON). However, large-scale population-based evidence on long-term trends in optic n...

Clinical outcomes and diagnostic stability in first-episode other specified schizophrenia spectrum and other psychotic disorder: evidence for a distinct clinical entity

Research on the clinical outcomes and diagnostic stability of first-episode other specified schizophrenia spectrum and other psychotic disorder (FE-OSSO) remains very limited. This study was conducted to identify baseline demographic and clinical features and cognitive function,...

SimpleMicrobiome: An integrated web-based platform for streamlined microbiome data analysis and visualization

Microbiome studies require multiple analytical steps after initial sequence processing. These steps commonly include data harmonization, preprocessing, taxonomic profiling, diversity analysis, differential abundance testing, predictive modeling, network inference, and preparation...

Korean Clinical Practice Guidelines for Rehabilitation in Critically Ill Patients and Post-Intensive Care Syndrome

Background: Survivors of critical illness commonly experience persistent physical, cognitive, and psychological impairments, collectively known as post–intensive care syndrome. Although intensive care unit (ICU) rehabilitation is now recognized as an important part of recovery af...

Cone-Beam Computed Tomography-Based Evaluation of Immediate Maxillary Transverse Changes Following Invisalign Palatal Expander in Mixed-Dentition Patients: A Three-Case Series

Maxillary constriction in the mixed dentition is commonly associated with a narrow arch form, space deficiency, and impaired eruption guidance. Although the use of the Invisalign Palatal Expander has increased in growing patients, case-based evidence regarding its immediate skele...

Identification of a Pathogenic RECQL4 1.6-kb Deletion–Insertion in a Neonate with Atypical Skeletal Phenotype of Baller–Gerold Syndrome Using Rapid Whole-Genome Sequencing

Mi-Ae Jang, M.D., Ph.D., Ja-Hyun Jang, M.D., Ph.D., Jin Kyu Kim, M.D., Ph.D., Joonhong Park, M.D., Ph.D., Go Hun Seo, M.D., Ph.D., Misun Yang, M.D., Ph.D., Yun Sil Chang, M.D., Ph.D., and Hyun Ho Kim, M.D., Ph.D.. Ann Lab Med -0001;0:. https://doi.org/10.3343/alm.2026.0102