Institution
Jawaharlal Nehru Centre for Advanced Scientific Research
Recent research
- Materials & EnergyOpen access
Employing “FAST Water” to Accelerate Self-Assembly
Abstract Molecular dynamics (MD) simulations are a powerful tool for elucidating the molecular mechanisms of supramolecular self-assembly, but the long time scales of aggregation often make all-atom simulations computationally challenging. Here, we evaluate the recently developed...
- Physics & SpaceOpen access
Inverse Design of the Topology–Bandwidth Trade-Off in Valley Photonic Crystals
Abstract Valley photonic crystals provide a route to broadband domain-wall guiding, but increasing the bulk gap can delocalize Berry curvature and reduce the nonquantized valley-Chern number. We introduce a mixed-integer particle-swarm framework that searches polygonal VPC unit c...
Photo‐Induced Electrochromism: Toward a Self‐Coloring Smart Window
ABSTRACT Smart windows that dynamically regulate solar radiation are crucial for reducing building energy consumption. Electrochromic (EC) smart windows offer high‐performance optical modulation but require an external power supply, whereas photochromic (PC) smart windows are sel...
- Materials & EnergyOpen access
Transition in elastic Dean flow: the centre-mode versus hoop-stress pathways
We analyse the stability of viscoelastic Dean flow (flow of an elastic fluid through a curved two-dimensional channel, driven by an azimuthal pressure gradient) in the absence of fluid inertia. This configuration is well known to exhibit a hoop-stress-driven ‘purely elastic’ inst...
- Materials & EnergyOpen access
Tau aggregation into polymorphic species, including oligomers, fibrils, and neurofibrillary tangles (NFTs), is central to the pathology of Alzheimer’s disease and related tauopathies. As an intrinsically disordered protein, tau undergoes liquid-liquid phase separation (LLPS), a m...
- Materials & EnergyOpen access
Transformative Materials Research: Defining Conceptual Change across Scales
Abstract What qualifies as transformative materials research? In this Viewpoint, we use “transformative” to denote work that forces revision of underlying assumptions, enables generalization across systems, or reveals regimes inaccessible to existing frameworks. The term is widel...
- Biology
Guanidine-Functionalized Aminoglycosides Enable miR-7a Delivery to Attenuate Neuroferroptosis
Abstract Ferroptosis is an iron-dependent form of regulated cell death driven by lipid peroxidation and increasingly recognized as a key contributor to neurodegeneration (neuroferroptosis). Current pharmacological approaches primarily target downstream ferroptotic events and do n...
- BiologyOpen access
Abstract Increasing resistance to conventional antifungal drugs against Candida species, along with the limited availability of drug targets due to similarities between fungal and human cellular processes, necessitates alternative antifungal strategies. Chitin, a key polysacchari...
- Health & MedicineOpen access
Urolithin A mitigates behavioural and synaptic deficits associated with epilepsy
Abstract The persistence of drug-resistant epilepsy highlights the need for new therapeutic interventions that target novel mechanisms with homeostatic regulations while minimizing side effects. Slow-acting drugs, particularly small molecules of natural origin with anti-epileptog...
- BiologyOpen access
Genes transcribed by the RNA polymerase (Pol) III of yeast are mostly found at sites of high transcription, genomic fragility, and replication fork stalling. Transcription terminator–dependent facilitated recycling of Pol III on naked DNA templates boosts transcription in vitro;...
- Materials & Energy
Abstract Two-phase-engineered bimetallic alloys with tunable crystallographic defects offer a promising platform for proton-coupled electron-transfer in electrocatalytic nitrate reduction (NO3RR) to ammonia, providing a sustainable alternative to the Haber–Bosch process. Alloying...