Jawaharlal Institute of Post Graduate Medical Education and Research

Blood culture turnaround time and antimicrobial resistance following an operational research interventions at 37 Military Hospital, Ghana

We conducted a retrospective before and after comparative observational study using routinely collected hospital data from neonates with suspected sepsis admitted between January 2022 and July 2024. Outcomes were compared with a previous study (2017–2020) following implementation...

School-level clustering and individual correlates of adolescent substance use in India: a multicentre multilevel study

Adolescent substance use is a growing health burden in India, yet evidence mostly focuses on individual-level correlates while overlooking potential school-level heterogeneity and contextual characteristics within school settings. This study examined individual- and school-level...

[ 177 Lu]Lu‐PSMA‐617 Plus Short‐Course Priming With Enzalutamide in Metastatic Castration‐Resistant Prostate Cancer: A Single‐Arm Phase 2 Trial (Lu‐PRIME)

ABSTRACT Background [ 177 Lu]Lu‐PSMA‐617 has been an approved treatment modality for metastatic castration‐resistant prostate cancer (mCRPC). Recent studies have shown PSMA upregulation following enzalutamide, which may enhance the outcomes with [ 177 Lu]Lu‐PSMA‐617. This study a...

Religious Affiliation and Reported Dual Menstrual Material Use Among Young Women in India

Background: Dual-method menstrual hygiene use, defined as the use of both modern menstrual hygiene products (e.g., sanitary pads) and traditional materials (e.g., cloth), remains under-researched among young women in India. While socioeconomic factors are associated with menstrua...

SACNN: a spatial attentive 2D CNN for improved accuracy and interpretability in ECG image classification

Abstract Deep Learning models have shown strong performance in ECG analysis. However, many existing models operate as black-box systems or depend on post-hoc explainable techniques, limiting transparency. Moreover, attention-based mechanisms have focused on 1D ECG signals with li...

Opioid-Sparing Versus Opioid-Based Analgesia for Craniotomy: A Multicenter Randomized Controlled Trial

Introduction: Pain control remains a challenge after neurosurgery. Opioid-sparing analgesia may provide better pain relief without opioid-related side effects after craniotomy. We aimed to compare analgesia requirement and postoperative pain between opioid-sparing and opioid-base...

Quantitative morphometry of the cervix using deep learning and geometric area estimation techniques

Abstract Objective Estimation of the actual cervix area observed during the colposcopy is a critical step towards accurate diagnosis, as hidden areas may lead to malignancy in the future. In the present study, an automated algorithm was developed that uses a deep learning segment...

Feasibility of Telemedicine for Cancer Pain Management: A Pragmatic Randomised Controlled Trial

Objectives: To evaluate the feasibility of implementing telemedicine for cancer pain management through assessment of patient adherence, quality of life, and satisfaction with palliative care. Materials and Methods: Longitudinal open-label randomised controlled trial (n = 170). P...

Stroke-Like Cerebral Injury Following Mild Traumatic Brain Injury and Early Posttraumatic Seizures in an Infant: A Diagnostic Dilemma with Negative Vascular Imaging

Abstract Stroke-like cerebral injury following mild traumatic brain injury (TBI) in infants is exceedingly rare. We report a 10-month-old male infant who sustained mild TBI in a road traffic accident, presenting with a pediatric Glasgow Coma Scale of E4V4M6 and a brain computed t...

Barriers, Facilitators, Attitudes, and Preferences Toward Digital Mental Health Interventions Among Patients with Severe Mental Illness and Their Caregivers: A Qualitative Exploration from a Low- and Middle-income Setting

Background: Digital mental health interventions (DMHIs) offer a potential solution to bridge the considerable treatment gap in mental health service delivery. Our objectives were to qualitatively examine barriers, facilitators, attitudes, and preferences toward DMHIs among patien...

Performance of IMACS MalignancyRisk Stratification in Idiopathic Inflammatory Myopathies:A Single-centre RetrospectiveCohort Study from India

Background: Idiopathic inflammatory myopathies (IIMs) carry an increased malignancy risk. Although the International Myositis Assessment and Clinical Studies Group (IMACS) has proposed guidelines to screen malignancies, their applicability across populations remains uncertain. In...

Multiparameter urine reagent strips for bedside identification of cerebrospinal fluid in epidural catheter aspirates: a proof-of-concept observation

Aspiration of clear fluid from an epidural catheter is a recurring, high-stakes clinical challenge. It may be residual saline from loss of resistance, local anesthetic (LA), or cerebrospinal fluid (CSF)—all visually indistinguishable. This matters because a full epidural LA dose...

Low cost app-based intervention DIALOG+ for anxiety and depression in outpatient psychiatric settings: a pragmatic multisite cluster randomized controlled trial

Clinically diagnosed anxiety and depressive disorders are widely recognized as the most common mental health issues in India, affecting approximately 15% of the population. With notable gender disparities, Tamil Nadu has some of the highest depression rates in the nation. Despite...