Japanese Red Cross Society, Japan

Latent space structure of retinal age: an artificial intelligence–based analysis of aging in fundus images

Abstract This study investigated whether age-related variation is organized as a geometric structure in latent space and how fine-tuning reshapes this representation. Fundus photographs from fellow eyes of patients who underwent macular surgery were retrospectively analyzed. Afte...

Relationship between initial dose, dose intensity, and survival in unresectable pancreatic cancer treated with nanoliposomal irinotecan, fluorouracil, and folinic acid

Abstract While nanoliposomal irinotecan with fluorouracil and folinic acid (NFF) is a standard second-line regimen for unresectable pancreatic cancer (uPC) after gemcitabine-based therapy, the effects of initial dosing and relative dose intensity (RDI) in routine practice are unc...