Japan Science and Technology Agency

Antibacterial and Biocompatible Iodine-Releasing Polycationic Coatings Synthesized by Solvent-Free Initiated Chemical Vapor Deposition

Abstract Bacterial adhesion to surfaces of medical devices may cause medical device-associated infections. This challenge can be addressed by surface modification utilizing antibacterial coatings. Polycationic coatings possess excellent antibacterial activity, but their biocompat...

Structural and Mechanistic Basis of Bacterial 2-Methyl-ACC Synthases

Abstract Cyclopropane-containing amino acids are found in diverse natural products and contribute to their structural complexity and biological activity. However, the distribution of bacterial biosynthetic pathways that produce methylated cyclopropane amino acids and the structur...

Complementary Hydrogel-Based Ionic Thermoelectric Systems for Photovoltaic Waste Heat Harvesting and Energy Storage

Photovoltaic (PV) operation generates substantial low-grade waste heat, motivating energy-recovery strategies that can accommodate dynamically varying thermal conditions. Here, thermogalvanic and thermodiffusive hydrogel-based ionic thermoelectric (iTE) devices were separately in...

Targeting the Zinc Metalloproteinase Superfamily in the CNS: Medicinal Chemistry Strategies To Optimize Selectivity, Pharmacokinetics, and Blood–Brain Barrier Permeability

Abstract The zinc metalloproteinase superfamily [matrix metalloproteinases (MMPs), a disintegrin and metalloproteinases (ADAMs), and ADAMs with thrombospondin motifs (ADAMTSs)] represents a high-value yet elusive therapeutic target for peripheral disorders and central nervous sys...

Crystallographic Spin‐Orbit Torque From Epitaxial CrSb

ABSTRACT Altermagnets (AMs) represent an emerging magnetic phase that combines compensated antiferromagnetic order with ferromagnet‐like spin‐splitting, offering a new route for efficient spin‐current generation. Here, we experimentally demonstrate spin‐torque generation in epita...

Discovery of an intrinsic non-Hermitian phase transition in a bulk condensed-matter system

Across regular phase transitions, systems remain in thermal equilibrium. However, when a system is driven far from equilibrium, non-Hermitian phase transitions may arise where the dynamical behavior—rather than steady properties—undergoes a qualitative change at a critical, so-ca...

Development of a Photostable pH Biosensor Based on mStayGold

Fluorescent proteins (FPs) that are pH-sensitive play a crucial role in investigating pH-related cellular processes, such as endocytosis and exocytosis. Existing pH-sensitive FPs generated from Aequorea victoria green fluorescent protein (GFP), such as superecliptic pHluorin (SEP...

SoccerSynth-detection: a synthetic dataset for soccer player detection

Abstract Soccer player detection is a fundamental task in soccer video analysis, supporting downstream applications such as event analysis and tactical reconstruction. However, annotated soccer player data from broadcast videos are difficult to obtain and use at scale because of...

Dynamic helical poly[4]helicene nanoribbon

<title>Abstract</title> The precise synthesis of helical graphene nanoribbons (GNRs) with a controlled handedness has a transformative potential as the promising chiral carbon materials. We now report the first synthesis of a dynamic helical poly[4]helicene nanoribbon, a novel cl...

Polymerization as a structuring strategy for hierarchical order and function

Abstract Polymerization has long been used as a tool for structural fixation: liquid or soft precursors are converted into solids. Recent advances in polymerization-based processing technologies have greatly expanded this role, now allowing complex external architectures to be in...