Jan Kochanowski University

Depressive Symptoms in Adults with Obesity and Their Associations with Sociodemographic, Health and Lifestyle Factors: A Secondary Analysis of a Cross-Sectional Study

Background/Objectives: Research indicates a bidirectional association between obesity and depression. The co-occurrence of both disorders has serious clinical implications. The aim of this study was to assess the prevalence of self-reported depressive symptoms (DS) in a group of...

Explained and Residual Variability of the Fetal Mechanical PR Interval in Structurally Normal Hearts: A Secondary Analysis of Physiological, Biometric, and Doppler Covariates

Background/Objectives: A previous publication reported that routinely measured covariates explained approximately 10% of fetal mechanical PR interval (mPR) variance. This secondary analysis examined how explanatory information is distributed among correlated predictors, their inc...

Empirical Antibiotic Initiation for Suspected Early-Onset Neonatal Infection in the Setting of Maternal GBS Screening and Intrapartum Antibiotic Prophylaxis: A Single-Center Retrospective Cohort Study

Background and Objectives: Maternal Group B Streptococcus (GBS) screening and intrapartum antibiotic prophylaxis have reduced early-onset GBS disease. However, suspected early-onset neonatal infection (EONI) remains a broader clinical challenge, as signs prompting empirical antib...

Emergency abdominal surgery: variation in closure practice and early postoperative outcomes in the prospective multicentre PROPHECY study

Emergency abdominal surgery carries a high risk of postoperative morbidity, yet prospective multicentre data on real-world abdominal wall closure practices remain limited. This interim analysis of the PROPHECY study aimed primarily to characterise current abdominal wall managemen...

The accretion rate resulting in the initial mass function

Abstract The aim of this study is to provide a description of the stellar initial mass function (IMF) using the framework of non-extensive statistical mechanics. We seek to demonstrate that the Tsallis distribution, characterized by a single analytical form, can successfully repr...

Difficult relationships between humans and bacteria: associations between multiple sclerosis and the human microbiome

Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system, the pathogenesis of which involves complex interactions between genetic predisposition, environmental factors, and dysregulation of immune responses. This review critically synthesizes ava...

Metacognition and Self-Disturbances in Schizophrenia: Implications for Psychological and Neurocognitive Therapy

Background/Objectives: Schizophrenia is a complex psychiatric disorder characterized by positive, negative, and cognitive symptoms, as well as disturbances of the self and metacognitive dysfunction. Increasing evidence suggests that these dimensions contribute substantially to ps...

Physical Activity–Sedentary Behaviour Profiles and Co-Occurring Lifestyle Behaviours Among Adolescents: A Person-Oriented Analysis

Background/Objectives: Physical activity and sedentary behaviour are important components of adolescent lifestyle, but favourable movement behaviour may not correspond to favourable behaviours across other health-related domains. This study aimed to identify empirical physical ac...

Sustainable Waste-Derived Mineral–Carbon Composites as Reusable Sorbents for Solid-Phase Extraction of Selected Organophosphorus Pesticides from Water

Organophosphorus pesticides (OPs) are persistent environmental contaminants requiring monitoring in aquatic ecosystems. In this study, four novel mineral–carbon composites (K-HNT, K-C-HNT, D-HNT, and D-C-HNT) were synthesized via thermal treatment at 800 °C from halloysite nanotu...

Clinical characteristics associated with failure to achieve a prespecified guideline-directed medical therapy target at discharge in patients with HFrEF undergoing scheduled hospitalization: a secondary analysis of the HEROES study

Abstract Guideline-directed medical therapy (GDMT) is crucial for the pharmacological management of heart failure (HF) with reduced ejection fraction (HFrEF). The aim of the study was to identify clinical characteristics associated with failure to achieve the prespecified stringe...

Recommendations of Multiple Sclerosis and Neuroimmunology Section of the Polish Neurological Society and the Polish Society of Gynecologists and Obstetricians for family planning and pregnancy management in women with multiple sclerosis: an update

INTRODUCTION: Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease of the Central Nervous System that most commonly affects females of reproductive age. Therefore, the issue of family planning is relevant in this population, especially in the context of starting a...

Mammography-Based Radiomics for Prediction of Nodal Status and Disease Burden in Breast Cancer: A Temporally Validated Study

Objectives: We evaluated the performance of mammography-based radiomics in prediction of clinical nodal status, clinical tumor stage, clinical disease stage, status of the PIK3CA mutation and concordance with the radiologist-assessed BI-RADS category. Mammography is often the fir...

Evaluation of the INTERGROWTH-21st fetal growth standards in a single-center cohort of uncomplicated pregnancies in Poland

OBJECTIVES: To evaluate the applicability of the INTERGROWTH-21st prescriptive fetal growth standards for thirdtrimester biometry and estimated fetal weight (EFW) assessment in a Polish population. MATERIAL AND METHODS: This retrospective single-center cohort study included 594 u...