Jahrom University of Medical Sciences

Performance of machine learning (ML) and deep learning (DL) algorithms in prediction of breast cancer distant metastasis via imaging: a systematic review and meta‑analysis

Distant metastasis is a major cause of breast cancer mortality. Early prediction may support risk-adapted surveillance and treatment planning. We evaluated imaging-based machine learning (ML) and deep learning (DL) models for predicting future distant metastasis in patients witho...

Targeting ferroptosis in cancer: molecular mechanisms and emerging therapeutic strategies

Ferroptosis, an iron-dependent form of regulated cell death characterized by the lethal accumulation of lipid peroxides, has emerged as a pivotal pathway in cancer biology and a promising therapeutic target. This review synthesizes the core molecular machinery governing ferroptos...

Satisfaction of antenatal care services and its associated factors among pregnant women in selected public health facilities in Kandahar, Afghanistan

Research indicates that satisfaction with antenatal care (ANC) services remains suboptimal across several low-and middle-income countries (LMICs). However, there is a research gap on the satisfaction of ANC services in Afghanistan. Therefore, this study aims to assess satisfactio...

Electronic Nicotine Delivery Systems Use Among Students in the Eastern Mediterranean Region: A Systematic Review and Meta-Analysis of 60 Studies on Prevalence and Socioeconomic Determinants

Background The rapid global increase in Electronic Nicotine Delivery Systems (ENDS) use among youth is a pressing public health concern. However, comprehensive data for the Eastern Mediterranean Region (EMRO) remains sparse. This study aimed to conduct a systematic review and met...

The effect of music on breast milk volume in mothers of neonates admitted to the neonatal intensive care unit: a systematic review and meta-analysis

Abstract Background Mothers of neonates admitted to the neonatal intensive care unit typically experience higher levels of anxiety and stress due to early separation from their infant, the critical condition of the neonate, psychological stressors, and dependence on mechanical br...

Development and validation of a questionnaire for diabetes prevention behaviors based on the behavior change wheel framework in Iranian adults with prediabetes

The rising prevalence of prediabetes necessitates theory-based instruments to assess behavioral determinants and guide prevention. This study developed and validated a questionnaire based on the Behavior Change Wheel (BCW) for Iranian adults with prediabetes. This cross-sectional...

The effect of microlearning on nursing students’ knowledge and satisfaction in psychiatric emergencies education: a quasi-experimental study

Abstract Background Psychiatric emergencies, including suicidal behaviors, violence, and delirium, are complex conditions that require prompt intervention. Nurses and nursing students play a key role in the early identification and management of these situations; however, traditi...

Global prevalence of colistin resistance, mcr gene variants, and sequence types in Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, and Stenotrophomonas maltophilia: a systematic review and meta-analysis

Abstract Background Due to the increasing prevalence of infections caused by multidrug-resistant (MDR) Gram-negative bacteria, colistin has become an important therapeutic option. However, the rapid emergence of resistance to this antimicrobial agent, mediated by mechanisms such...

Incremental Prognostic Value of CT Indices Derived from Midline Shift and Hematoma Thickness in Acute Subdural Hematoma

Background: In acute subdural hematoma (ASDH), early risk stratification relies heavily on hematoma thickness (HT) and midline shift (MLS). Composite indices derived from these measures have been proposed to better characterize mass effect, but their incremental prognostic value...

Comparison of novel visceral adiposity indices with body mass index for identification of prevalent diabetes: findings from the 2021 Iran STEPS survey

Diabetes mellitus (DM) is a major contributor to global morbidity and mortality, particularly in developing regions. Effective identification of high-risk individuals is crucial for targeted prevention and resource allocation. This population-based study aimed to compare the asso...

Bioinformatics Identification of lncRNA‐Associated Molecular Signatures Potentially Related to Quercetin Response in Breast Cancer

ABSTRACT Breast cancer affects approximately one in every eight women globally, as reported by the World Health Organization. Among all female malignant tumors, breast cancer has the highest fatality rate, surpassed only by lung cancer. Advanced stages of this disease are almost...

Association between gestational diabetes mellitus and adverse pregnancy outcomes and effect modification by maternal age in a population based cohort study

Abstract Gestational diabetes mellitus (GDM) is a rising public health issue and comes with many negative pregnancy effects for both mothers and infants. Because there is an increasing pattern in advanced maternal age around the globe, it has become very important to know whether...

Multimodal transformer-enhanced deep learning for accurate assessment of mandibular third molar–inferior alveolar canal contact using panoramic radiography and CBCT slices

Accurate preoperative assessment of the spatial relationship between mandibular third molars (M3Ms) and the inferior alveolar canal (IAC) is essential to minimize the risk of nerve injury. While panoramic radiographs (PRs) are routinely used as a first-line modality, their two-di...

Enhancing geriatric perioperative care competencies through structured, geriatric-focused clinical rounds for operating room nursing students: a quasi-experimental study

The growing number of older adults undergoing surgery highlights the need for strengthened geriatric competencies among operating room (OR) nursing students. Despite this demand, geriatric-focused perioperative training remains limited in OR curricula. This study examined the eff...

The janus-faced function of mesenchymal stem cells in oral cancer

Mesenchymal stem cells (MSCs), which exist in bone marrow, tooth pulp, and tumor microenvironments, have a dual role in oral malignancies. These cells interact closely with cancer stem cells (CSCs) and the tumor microenvironment (TME). On the one hand, MSCs accelerate the growth...

Plasma p-tau217 as a two-cutoff approach to improve tau-PET screening and trial recruitment in Alzheimer’s disease

Abstract Blood-based biomarkers could broaden access to Alzheimer’s disease diagnostics, but their ability to approximate tau PET, and to address gray-zone results, remains uncertain. We evaluated plasma p-tau217 against tau PET using a harmonized ADNI baseline cohort and an inde...

Coverage and factors associated with receipt of early newborn postnatal care components in Afghanistan: findings from the 2022–2023 multiple indicator cluster survey

BACKGROUND: Neonatal mortality remains high in low‑ and middle‑income countries, where early postnatal care (PNC) within 48 hours can avert many deaths. Yet neither the national coverage of newborn PNC nor the factors associated with its receipt have been assessed. OBJECTIVES: We...