Izumi City General Hospital

Quality of Life and Physical Status Among Individuals with Alcohol Dependence Before, During, and After the COVID-19 Pandemic: A Repeated Cross-Sectional Study

We examined changes in psychological and physical status among individuals with alcohol dependence before, during, and after the COVID 19 pandemic, aiming to identify factors related to quality of life (QOL) and hepatic reserve. We conducted a retrospective repeated cross-section...

A multicenter phase II trial of ramucirumab plus irinotecan for early recurrence of gastric cancer during or after adjuvant chemotherapy with docetaxel plus S-1 therapy: the RAMIEL trial (OGSG1901)

Abstract Background There is currently no established chemotherapy regimen for early recurrence of pathological stage III gastric cancer (GC) following adjuvant chemotherapy with docetaxel plus S-1 (DS) after D2 gastrectomy. We aimed to evaluate the efficacy and safety of ramucir...

Relationship between initial dose, dose intensity, and survival in unresectable pancreatic cancer treated with nanoliposomal irinotecan, fluorouracil, and folinic acid

Abstract While nanoliposomal irinotecan with fluorouracil and folinic acid (NFF) is a standard second-line regimen for unresectable pancreatic cancer (uPC) after gemcitabine-based therapy, the effects of initial dosing and relative dose intensity (RDI) in routine practice are unc...

Retrograde carotid fat pad flip method for carotid exposure during carotid endarterectomy

Background: Exposure of the distal internal carotid artery (ICA) during carotid endarterectomy (CEA) can be challenging in anatomically difficult cases. We present the retrograde carotid fat pad (CFP) flip method, a cranial-first, layer-oriented exposure strategy based on preserv...