Izmir Tepecik Eğitim ve Araştırma Hastanesi

Inflammatory and Nutritional Indices Associated with Histopathological Severity of Cervical Lesions in HPV-Positive Women

Abstract Objective This study aimed to evaluate the association of inflammatory and nutritional indices, including HALP (Hemoglobin × Albumin × Lymphocyte / Platelet), neutrophil-to-lymphocyte ratio (NLR) and systemic immune-inflammation index (SII), with cervical intraepithelial...

Tranexamic acid in proximal femoral megaprosthetic reconstruction for metastatic bone disease

This retrospective comparative study evaluated the effect of tranexamic acid (TXA) on perioperative transfusion requirements and clinically documented thromboembolic events in patients undergoing proximal femoral tumor resection and megaprosthetic reconstruction for metastatic bo...

Assessment of nutritional risk and associated determinants in adult intensive care unit patients: a prospective longitudinal observational study comparing NRS-2002 and mNUTRIC

Background: Malnutrition is common in critically ill patients and increases morbidity and mortality. Nutritional assessment is a fundamental component of nursing care; therefore, early identification of nutritional risk is essential for timely interventions in intensive care unit...

Relationships between Continuous Glucose Monitoring-Derived Glycemic Parameters and Early Retinal Vascular Changes in Children with Type 1 Diabetes Mellitus

Objective: This study investigated relationships between continuous glucose monitoring (CGM)-derived metrics and early retinal vascular changes in children having type-1 diabetes mellitus (T1DM) with no clinically-visible diabetic retinopathy (T1DM-noR). Methods: Forty-two T1DM-n...

Genotype–cognitive phenotype associations in Duchenne muscular dystrophy: the role of mutation location and ambulatory status in a pediatric cohort

Duchenne muscular dystrophy (DMD) is characterized by progressive motor decline as well as cognitive impairment and reduced quality of life. This study aimed to investigate the relationship between genotype, cognitive functioning, and quality of life in children with DMD. This cr...

Turkish Cross-Cultural Adaptation of the BRIEF-MPI in Older Adults with Cancer: Convergent and Discriminative Validity Compared with the G8 and Clinical Frailty Scale

Background: Older adults with cancer represent a heterogeneous population with varying levels of frailty and multidimensional vulnerability. Rapid screening tools are needed to identify patients who may benefit from comprehensive geriatric assessment (CGA). This study aimed to tr...

Visual and Semiquantitative Assessment of 123I-Ioflupane SPECT in Probable Dementia with Lewy Bodies and Its Association with Autonomic Dysfunction: A Retrospective Study

Background/Objectives: Dementia with Lewy bodies (DLB) is a clinically heterogeneous neurodegenerative disorder characterized by cognitive, neuropsychiatric, motor, and autonomic manifestations. Reduced striatal dopamine transporter availability on 123I-ioflupane single-photon em...

Endoscopically assisted decompression in cubital tunnel syndrome: clinical and electrophysiological evaluation

Aim: Endoscopic decompression has become an increasingly popular technique for cubital tunnel syndrome in recent years. This study aimed to report the clinical and electrophysiological outcomes of patients treated with the endoscopy-assisted decompression technique for cubital tu...

Impact of adjuvant endocrine therapy on disease-free survival in early triple-positive breast cancer: a multicenter retrospective cohort study of the Turkish oncology group

Triple-positive breast cancer (TPBC), characterized by concurrent ER, PR, and HER2 positivity, poses unique therapeutic challenges due to ER–HER2 crosstalk. The optimal adjuvant endocrine therapy in TPBC patients receiving anti-HER2 regimens remains poorly defined. This multicent...