Istituto Nazionale di Riposo e Cura per Anziani

Impact of live-in care workers on health and well-being of older people with long-term care needs and their primary informal care providers during the Covid-19 pandemic in Italy

This study aimed to assess the impact of privately hired live-in care workers (LICWs), many of whom have a migrant background, on overall health status, emotional/psychological status and quality of life of older people with long-term care (LTC) needs and their primary informal c...

Organizing healthcare delivery in the era of disease-modifying therapies for Alzheimer’s Disease: an Italian RAND/UCLA consensus

BACKGROUND: Alzheimer's disease (AD) poses a growing clinical and organizational challenge, requiring coordinated, multidisciplinary care models. In Italy, significant regional variability in resources and access to diagnostic services persists, while the implementation of commun...

Impact of GLP-1 Receptor Agonists on Cognitive Performance in Adults at Risk of Alzheimer’s Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Background/Objectives: Type 2 diabetes, a widely recognized risk factor of Alzheimer’s disease (AD), is mainly due to the role played by insulin resistance on neuronal degeneration. Mild Cognitive Impairment (MCI) also significantly increases the risk of developing AD by approxim...

Interest in geriatric medicine training among health and social care professionals: the roles of experience and attitudes. Findings from the online survey of the COST Action PROGRAMMING 21122

Abstract Background The growth of ageing populations is increasing the requirement for professionals trained to care for older adults. Aims To explore factors associated with interest in further training in geriatrics across health and social care professionals. Methods The COST...

Extracorporeal Free-Light-Chain Removal in Myeloma Cast Nephropathy: Plasma Exchange and Hemodialysis Strategies in the Era of Effective Antimyeloma Therapy

Renal impairment affects up to half of patients with newly diagnosed multiple myeloma, and roughly 2–4% require dialysis at presentation, most often because of light-chain cast nephropathy. In these patients, renal recovery is associated with the speed and magnitude of serum free...

Personalized Sequential Nephron Blockade for Diuretic Resistance in Acute Decompensated Heart Failure: A Narrative Review for the Cardiorenal Clinician

Heart failure affects more than 64 million people worldwide, and admissions for acute decompensation account for a substantial proportion of cardiovascular healthcare expenditure. Achieving complete decongestion remains the principal objective of inpatient management, yet many pa...

Development and Internal Validation of a Clinical Risk Score for Hypovitaminosis D in Italian Adults Aged ≥50 Years Attending Osteoporosis and Metabolic Bone Disease Centers

Background/Objectives: Hypovitaminosis-D is a highly prevalent condition worldwide, associated with adverse skeletal and extra-skeletal outcomes. Increasing demand for serum 25-hydroxyvitamin D (25(OH)D) testing points toward the need for simple tools to identify individuals at r...