IQVIA (United Kingdom)

Organizing healthcare delivery in the era of disease-modifying therapies for Alzheimer’s Disease: an Italian RAND/UCLA consensus

BACKGROUND: Alzheimer's disease (AD) poses a growing clinical and organizational challenge, requiring coordinated, multidisciplinary care models. In Italy, significant regional variability in resources and access to diagnostic services persists, while the implementation of commun...

Association between introduction of 13-valent pneumococcal conjugate vaccine and burden of hospitalized adult pneumococcal disease in South Korea – a population-based retrospective database study

Abstract Background Information on the burden of pneumococcal disease and its association with vaccination in South Korea remains limited. This study aims to examine the incidence rate, case fatality rate, healthcare resource utilization and costs of pneumococcal disease in adult...

Metagenomic and Metabolomic Signatures of Gut Microbiota After Helicobacter pylori Eradication Therapy Supplemented with Butyric Acid and Inulin: Observational Study

The long-term impact of eradication therapy for Helicobacter pylori on the gut microbiota is a subject of significant interest. To evaluate the influence of the bismuth-based quadruple H. pylori eradication therapy supplemented with butyrate and inulin on functional alterations w...

Early versus delayed or no empagliflozin initiation after hospitalisation for heart failure in the United States: A target trial emulation

BACKGROUND: Sodium-glucose cotransporter-2 inhibitors (SGLT2is) are a foundational therapy for heart failure (HF), yet initiation is frequently delayed in clinical practice. Evidence comparing outcomes associated with early versus delayed or no initiation following hospitalisatio...

Burden of respiratory syncytial virus (RSV) hospitalizations among adults aged 60 years or more in Brazil: A retrospective surveillance database analysis (2013–2024)

Background Globally, respiratory syncytial virus (RSV) is a leading cause of severe respiratory illness in adults aged ≥60 years. Risk increases with advancing age and comorbidities, particularly cardiopulmonary disease and diabetes. RSV disease burden in adults is often underest...

Dupilumab exposure and herpesvirus infection risk in atopic dermatitis: A claims‐based cohort study

The data that support the findings of this study were obtained under a contract with IQVIA Solutions Japan G.K. and are not publicly available. Data may be available from IQVIA Solutions Japan G.K. subject to applicable permissions, contractual restrictions, and privacy or ethica...

Assessing Value of Behavioral Interventions: Designing Cost-Effectiveness Analyses for Food-Is-Medicine Interventions

Food-is-Medicine (FIM) interventions, including medically tailored meals, medically tailored groceries, and produce prescriptions, represent a promising approach to prevent, manage, and treat diet-related diseases. As the evidence base for FIM interventions expands through large-...

Tozorakimab to Prevent COPD Exacerbations

BACKGROUND: Many patients with chronic obstructive pulmonary disease (COPD) have exacerbations despite receiving standard-of-care inhaled maintenance therapy. Dysregulated interleukin-33 signaling is implicated in the pathogenesis of COPD. Tozorakimab is a monoclonal antibody tha...

Hospital Length of Stay and Associated Factors in Patients with Oral Cavity Cancer in Germany: A Retrospective Multicenter Analysis of Inpatient Administrative Data

Background: Oral cavity cancer is a clinically relevant subgroup of head and neck malignancies and is associated with substantial treatment burden and healthcare utilization. Hospital length of stay (LOS) is an important indicator of inpatient resource use and complexity of care,...

Investigating patients’ experiences with dyspnea associated with warm autoimmune hemolytic anemia (wAIHA) and cognitive debriefing of the FACIT-Dyspnea 10-item short form: a qualitative patient interview study

Abstract Background Dyspnea is a prominent symptom in patients with warm autoimmune hemolytic anemia (wAIHA), yet its lived experience remain under-researched. Although clinically relevant, dyspnea is not routinely assessed in wAIHA trials, and no validated patient-reported outco...

Multi-SALLM: a multilingual security assessment of generated code

Abstract As Large Language Models (LLMs) become increasingly integrated into software engineers' daily workflows, it is critical to ensure the code they generate is not just functionally correct but also secure. While LLMs can boost developer productivity, prior empirical studies...

Psychological symptoms in individuals with Spinal Muscular Atrophy (SMA) and their caregivers – results from a nation-wide study in Germany

Abstract Background This study investigates the prevalence and associations of psychological symptoms in individuals with Spinal Muscular Atrophy (SMA) and their caregivers, utilizing data from a cross-sectional, observational assessment conducted in Germany. Participants were re...