International Vaccine Institute

Establishment of a CD46 and desmoglein-2 expressing mouse model for human adenovirus type 55 vaccine evaluation

Human adenovirus type 55 (HAdV-55) is an emerging respiratory pathogen associated with severe pneumonia, for which no licensed vaccines are currently available. The lack of physiologically relevant small-animal models has limited preclinical evaluation of vaccine candidates. In t...

Phylogenomics and antimicrobial resistance genes of invasive non-typhoidal Salmonella in the Ashanti region of Ghana

Abstract Background Invasive non-typhoidal Salmonella (iNTS) disease is a major public health threat in developing countries, yet molecular epidemiological data from Ghana remain limited. This study characterizes the phylogenomic profiles and antimicrobial resistance determinants...