International Renal Research Institute of Vicenza

Prognostic Role of Adverse Events in a Worldwide Population of Patients with Biliary Tract Cancer Treated with Chemo-Immunotherapy

Background: Biliary tract cancers (BTCs) are aggressive malignancies with limited treatment options. The addition of durvalumab or pembrolizumab to cisplatin–gemcitabine improves overall survival (OS), but validated biomarkers of benefit remain limited. Immune-mediated adverse ev...

Mapping HIV infection and sex-based differences among sub-Saharan African migrants in Northeast Italy: a multicenter study

HIV continues to disproportionately affect Sub-Saharan African (SSA) migrants in Italy, who often experience late diagnosis and complex clinical and social challenges. This multicenter cross-sectional study evaluated determinants of poor immunological and virological outcomes and...

Acute kidney injury and renal replacement therapy: a critical synthesis of metabolic derangements and nutritional implications

Acute kidney injury (AKI) affects up to 50% of critically ill patients and is frequently complicated by severe metabolic derangements, requiring the initiation of replacement therapy (RRT) in 10–15% of cases. Despite substantial progress in the diagnosis of AKI and optimisation o...