Institutul Regional de Oncologie

Preoperative Upper Gastrointestinal Endoscopy in Metabolic and Bariatric Surgery: A Narrative Review of Current Evidence and Clinical Recommendations

Metabolic and bariatric surgery (MBS) represents the most effective therapeutic approach for achieving substantial and sustained weight loss and improving obesity-related comorbidities. However, the role of routine preoperative esophagogastroduodenoscopy (EGD) remains controversi...

Diagnostic and Management Challenges in Mixed-Source MDR Sepsis in a Kidney Transplant Recipient with an Infected Sacral Pressure Ulcer Treated with VAC Therapy: A Case Report

Background: Kidney transplant recipients are particularly vulnerable to severe infections because of chronic immunosuppression, impaired wound healing, repeated healthcare exposure, and the potential nephrotoxicity of antimicrobial therapy. We report a complex case of multidrug-r...

Nonfatal Burden of Disease and Risk-Attributable Burden in Romania, 1990 to 2023: A Secondary Analysis of Global Burden of Disease 2023 Estimates

Background/Objectives: We assessed changes in nonfatal disease burden and risk attribution in Romania between 1990 and 2023. Methods: We analysed Global Burden of Disease (GBD) 2023 estimates of years lived with disability (YLDs), related nonfatal measures and risk attribution fo...

Spiritual Well-Being as a Patient-Reported Assessment Dimension in Advanced Cancer: Clinical Validation and Quality-of-Life Implications

Background: In advanced cancer care, routine clinical assessment often focuses on symptoms, treatment tolerance, and disease status, while spiritual well-being remains insufficiently explored despite its relevance to quality of life (QoL). Standardized patient-reported tools may...

Maternal Cardiovascular Phenotype in Fetal Growth Restriction with or Without Pre-Eclampsia: Insights from Echocardiography and Clinical Implications

Fetal growth restriction (FGR) has traditionally been attributed to placental insufficiency. However, accumulating evidence suggests that maternal cardiovascular maladaptation contributes to disease expression, clinical heterogeneity, and long-term maternal cardiovascular risk. T...