Institutul Regional de Gastroenterologie Prof. Dr. Octavian Fodor

Metabolic Syndrome and Pancreatic Cancer: Linking Insulin Resistance, Inflammation, and Carcinogenesis

Metabolic syndrome (MetS) is a composite classification defined by heterogeneous combinations of cardiometabolic abnormalities. Several components have been associated with pancreatic cancer (PC), but studies often conflate long-term metabolic exposure, tumor-related prediagnosti...

Comparison of the Alvarado Score with Alternative Diagnostic Tools in Pediatric Acute Appendicitis: A Literature Review

Background: Acute appendicitis is a leading pediatric surgical emergency. Timely diagnosis remains challenging, particularly in young children with atypical presentations. Clinical evaluation alone yields variable diagnostic performance, prompting the use of risk stratification t...

Beyond the biopsy: the new era of non-invasive staging and biomarkers in colorectal cancer

Colorectal cancer (CRC) management is increasingly challenged by shifting demographics, notably the rise in aggressive early-onset CRC, and the limitations of conventional anatomical staging. This comprehensive review explores the paradigm shift toward noninvasive and minimally i...