Instituto Nacional de Rehabilitación

A Proposed Convergent Genetic and Molecular Framework for Legg–Calvé–Perthes Disease: A Scoping Review

Legg–Calvé–Perthes disease (LCPD) is a rare pediatric disorder characterized by avascular osteonecrosis of the femoral head. Its pathogenesis is multifactorial, and genetic, epigenetic, vascular, and inflammatory mechanisms may contribute to disease susceptibility and progression...

Effects of rhythmic auditory stimulation on functional mobility and gait in individuals with Parkinson’s disease in a community environment

Objective To examine the effects of rhythmic auditory stimulation (RAS) on functional mobility and gait speed in Parkinson’s disease (PD) across indoor and supervised outdoor environments.Methods Of 52 individuals screened, 27 were enrolled in a repeated-measures design. Particip...

Connexin46-enriched extracellular vesicles facilitate cargo delivery and promote angiogenesis

Abstract Extracellular vesicles (EVs) are constantly released from cells. Their contents vary depending on conditions and cell type, influencing their effects on recipient cells. They have been implicated in several diseases, being currently recognized as key mediators of interce...

Isolation and Characterization of Lytic Bacteriophages Targeting Clinical Staphylococcus Other Than S. aureus

Abstract Staphylococcus spp., other than S. aureus (SOSA, formerly CoNS), are opportunistic pathogens often linked to biofilm infections on indwelling devices. Their rising antibiotic resistance highlights the need for novel therapies. Bacteriophages are promising due to their sp...

Anatomical Asymmetry in Adipose Tissue Thickness Alters Heat Transfer During Superficial Thermotherapy: A Computational and Experimental Study

Computer models and protocols commonly used for superficial thermotherapy assume anatomically symmetric tissue geometries. However, anatomical variability, particularly the variability of the adipose tissue thickness, may have a significant impact on heat transfer and cause non-u...

Segmental and Circumferential Hip Labral Reconstructions Both Show Favorable Outcomes in Primary Hip Arthroscopy: A Systematic Review

PURPOSE: To perform a systematic review comparing outcomes of segmental and circumferential hip labral reconstructions for irreparable labral tears. METHODS: A systematic search was conducted across PubMed, Embase, and CINAHL. The search terms used were "(hip OR hip arthroscopy)...

Translating the Properties of Physicochemical Dressings into Clinical Decision-Making for Heavily Exuding Wounds

Introduction: Heavily exuding wounds can macerate perilesional skin and favour infection. Information on the properties and use time of dressings should be clear and available to healthcare providers. Methods: Our aim was to evaluate the updated series of the AQUACEL® dressing fa...

Mexico’s First Heart Transplant in a Patient with Becker Muscular Dystrophy Reveals an Overlooked Cause of Idiopathic Dilated Cardiomyopathy

Background: Pathogenic variants in the DMD gene are a frequently overlooked cause of dilated cardiomyopathy (DCM) in idiopathic cases, especially when skeletal myopathy is mild or seemingly absent. Becker muscular dystrophy (BMD) and X-linked dilated cardiomyopathy are at opposit...