Instituto Federal de Educação, Ciência e Tecnologia do Pará

High Doses of N ‐Acetyl‐ P ‐Aminophenol Cause Acute Changes in Electroencephalographic and Electrocardiographic Activities in Wistar Rats

ABSTRACT N ‐acetyl‐ p ‐aminophenol (APAP), or acetaminophen, is the most prescribed analgesic and antipyretic, even used in association with other drugs. Because it is easily bought in drugstores, much evidence about its toxic effects is known due to high doses or continuous use,...

Green synthesis of gold nanoparticles from Pfaffia glomerata extracts for enhanced electrode modification and antimicrobial applications

Gold nanoparticles (AuNPs) are widely used in pharmaceuticals, diagnostics, textiles, and energy. Plant extracts have become a promising green alternative for AuNP synthesis. Pfaffia glomerata (Brazilian ginseng) contains phenolics and saponins that serve as reducing and stabiliz...

Cladocerans and macrophytes: network and resistance to extinctions

Abstract Macrophytes are important in structuring various aquatic communities, particularly cladocerans. Our findings highlight that plant structural complexity and functional life forms (specifically free-floating and submerged species) act as key drivers of interaction density...

Gross Agricultural Emissions and Unequal Mitigation Pathways in the Brazilian Legal Amazon: Implications for Climate Justice and the Sustainable Development Goals

ABSTRACT Climate mitigation policies in the Brazilian Legal Amazon have largely focused on aggregate or net emissions, providing limited evidence on how gross agricultural emissions reveal the intensity of productive emission sources independently of carbon removals. This gap con...

Advances in artificial intelligence and geomatics technology for the transformation of global agri-food systems: A review

Abstract The world’s rapidly growing population is driving up food demand and placing significant pressure on natural resources, posing major challenges to agricultural sustainability. Ensuring food security requires integrating innovative technologies that enhance productivity w...

Toxicological evidence that methylmercury exposure amplifies bone destruction and systemic impact associated with apical periodontitis in rats

Abstract This study investigated whether long-term methylmercury exposure aggravates apical periodontitis in Wistar rats. Thirty-two male rats (90 days old) were randomized into four groups (n = 8): control, methylmercury, apical periodontitis, and methylmercury + apical periodon...

Interventional tracheoscopy for management of intratracheal plasmacytoma in a dog

Abstract Intraoperative haemorrhage during interventional tracheoscopy for intratracheal masses can pose a life-threatening challenge. This report emphasizes the technical management of severe bleeding during endoscopic excision of a rare tracheal plasmacytoma in a dog, highlight...

Seven years of monitoring the demography and population density of jaguars (Panthera onca) in a human-modified landscape of eastern Amazonia

The primary impacts of mining on wildlife are habitat loss and fragmentation, which reduce the availability of essential resources and disrupt ecological processes necessary for species persistence. Despite the growing expansion of mining activities in tropical regions, their eff...

Exploring genetic variability in FOXE1 through in silico approaches: new insights on UTR variants

<title>Abstract</title> The <italic>FOXE1</italic> gene is a transcription factor critical for thyroid development and function, and has been associated with thyroid disorders and other phenotypic traits like cancer and orofacial clefts. This study explores the genetic variabilit...

Mapping the IntermolecularInteraction Landscape ina New Nicotinamide–Undecanoic Acid Cocrystal: SupramolecularStructure, Spectroscopic Analyses, and Computational Studies

Abstract A novel cocrystal composed of nicotinamide (NA) and undecanoic acid (UA) in a 1:1 stoichiometry has been successfully synthesized via slow evaporation and comprehensively characterized through a multidisciplinary approach combining experimental and computational methods....

Persistent Redox Imbalance in Post-COVID-19 Syndrome: Lipid Peroxidation, Antioxidant Enzyme Depletion, and Reduced Nitric Oxide Availability in an Amazonian Population

Post-COVID-19 syndrome (PCS) can persist even after mild acute illness, and oxidative stress has been proposed as a central mechanism for this persistence, although it remains poorly studied in the Amazon. This study characterized redox imbalance in patients with PCS through a co...