Instituto do Câncer do Estado de São Paulo

Screening strategies for the early detection of non-cardia gastric cancer in low- to moderate-prevalence regions: Asia-Pacific gastroesophageal cancer congress consensus 2026

Abstract Background Gastric cancer (GC) remains a major global health burden, and early detection is essential for improving patient outcomes. Although GC screening has been widely implemented in East Asian countries with a high disease burden, the optimal screening strategy for...

Differential associations between treatment delay and survival across head and neck cancer subsites: a national hospital-based framework for risk-stratified prioritization

Purpose Delays in time to treatment initiation (TTI) have been associated with inferior outcomes in head and neck cancer, yet prior studies have typically evaluated tumors collectively, assuming uniform time sensitivity across diseases. This study quantified subsite- and stage-sp...

Provox Life HMEs for Pulmonary Rehabilitation in HME ‐Naïve Laryngectomy Patients: A Randomized Controlled Trial

ABSTRACT Objective To evaluate whether Provox Life Heat and Moisture Exchangers (HMEs) and attachments enable HME‐naïve laryngectomized patients to establish a 24‐h HME routine, and whether the resulting effect on pulmonary symptoms is sustained over 9 months, compared with stand...

Prognostic factors for mortality and recurrence after radical nephroureterectomy for UTUC: a Brazilian cohort study

Abstract Purpose To evaluate the risk factors associated with mortality and recurrence following nephroureterectomy for upper tract urothelial carcinoma (UTUC) in a large Brazilian cohort. Methods This retrospective study analyzed 126 patients who underwent nephroureterectomy for...

Cannabis‐Based Oil for Pain and Other Non‐Motor Symptoms in Parkinson's Disease: A Randomized Controlled Trial

BACKGROUND: There is a lack of treatments for non-motor symptoms (NMS) in Parkinson's disease (PD). OBJECTIVE: To assess the safety and effectiveness of an oral Cannabis sativa L. extract on pain and other NMS of PD. METHODS: This phase II, randomized, placebo-controlled trial ev...