Instituto de investigación sanitaria y biomédica de Alicante

Cell Type‐Specific Extracellular Vesicles in Mouse Brain: Proteomic Signatures Highlight Astrocytic GlialCAM Network and GPCR Enrichment

Extracellular vesicles (EVs) mediate intercellular communication in the central nervous system (CNS) and are emerging as biomarkers of brain health and disease. However, the molecular composition of cell type-specific brain EVs, particularly astrocyte-derived EVs (ADEVs), remains...

Prevalence and incidence of dementia with Lewy bodies using current McKeith diagnostic criteria (2017–2020): a population-based study

Dementia with Lewy bodies (DLB) is one of the most common neurodegenerative dementias in older adults but remains frequently underdiagnosed in routine clinical practice. Epidemiological data are limited and heterogeneous, and only a small number of population-based studies have a...

Barriers and facilitators to advance care planning implementation: a qualitative interprofessional study in the Spanish public health and social care system

Advance Care Planning (ACP) is essential for improving the quality of end-of-life care. Despite having a well-established legal framework, the implementation of ACP in Spain is limited and largely bureaucratic. The existing literature has primarily focused on knowledge deficits a...