Instituto de Investigación Sanitaria Gregorio Marañón

Western diet induces MASLD and major transcriptional reprogramming in the liver-gut axis of early zebrafish larvae

Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD) is linked to western diet and sedentary lifestyle. While larval zebrafish are powerful discovery tools, standardized diets inducing early-stage MASLD are lacking. Here, we developed and early-stage zebrafis...