Instituto de Ciências Farmacêuticas

Thermal stability and CO₂ adsorption–desorption performance of synthetic hectorite and its CeO₂/NiO nanocomposites

Understanding the properties of clay minerals is crucial for developing efficient adsorbent and catalytic materials, creating new options for carbon capture technologies (CCT). This study investigates for the first time the thermal stability of synthetic hectorite (Hec), a smecti...

Bioactivity and nutritional profiling of underexplored unconventional food plants with potential for applications as functional foods

Abstract This study evaluated the bioactive and nutritional properties of six Amazonian unconventional food plants: Piper peltatum , Mansoa alliacea , Leuenbergeria bleo , Bidens bipinnata , Costus spiralis , and Urera caracasana . The phenolic compounds were identified and quant...

Untargeted LC-HRMS/MS and Feature-Based Molecular Networking Reveal Distinct Metabolic Signatures in Edible Dahlia Types

Abstract Edible flowers represent chemically diverse food matrices whose characterization increasingly relies on advanced metabolomic approaches. This study employed untargeted liquid chromatography–high-resolution tandem mass spectrometry (LC-HRMS/MS) combined with feature-based...

Healthcare occupancy data as an early warning indicator of infectious disease surges in São Paulo

Early detection of infectious disease surges is critical for effective public health response, yet traditional surveillance systems often suffer from delayed reporting. Here, we investigate whether passively collected occupancy data from healthcare facilities can act as an early...

Carbon balance in the Brazilian tropical dairy farming system

The expected increase in the global population is projected to raise the demand for milk and dairy products by 2050, highlighting the need to improve production efficiency while mitigating environmental impacts. This study evaluated the carbon balance of Brazilian tropical dairy...

Floral dynamics in the protandrous flowers of Bauhinia variegata (Fabaceae): phase-specific morphology, scent, and nectar production

Abstract Main conclusion Protandry in Bauhinia variegata is expressed through coordinated changes in floral morphology, scent composition, secretory activity, and nectar presentation, whereas petal reflectance remains stable; molecular docking further indicates that key phase-ass...

L-carnitine modulates molecular responses associated with inflammation, endoplasmic reticulum stress, and neurotrophic signaling in cerebral cortex of neonatal Gcdh−/− mice exposed to glutaric and quinolinic acids

Abstract Glutaric acidemia type 1 (GA I) is caused by deficient activity of glutaryl-CoA dehydrogenase, leading to predominant accumulation of glutaric acid (GA) in the brain. GA I patients present progressive neurological deterioration whose pathophysiology is only partially elu...