Instituto de Catálisis y Petroleoquímica

Integrating Drug Physicochemistry and Hfq-Dependent Regulation of Ciprofloxacin Accumulation in Escherichia coli

Ciprofloxacin (CIP), an amphoteric fluoroquinolone, undergoes pH-dependent changes in protonation state that influence membrane permeability and intracellular accumulation. Here, we investigated how drug physicochemistry and bacterial regulatory pathways jointly determine CIP acc...

Isolated Cu+–O–Ga3+ Pairs as Structural Motifs that Enhance CO2-to-Methanol Conversion

Abstract Isolated dual-atom sites constitute a promising yet largely unexplored strategy for directing reaction intermediates in CO2 hydrogenation to methanol. In this work, we identify isolated Cu+–O–Ga3+ dual-atom motifs and provide a mechanistically consistent interpretation l...