Institute of Physics

Enhanced pozzolanic activity of microcrystalline cellulose via silane modification for cementitious composites

Abstract This study evaluated the effect of surface functionalization of microcrystalline cellulose (MCC) with tetraethyl orthosilicate (TEOS) on its physicochemical properties and the performance of cement-based microconcretes incorporating the modified material. Eleven MCC samp...

A large-scale in silico chimera-based strategy for engineering low-immunogenic L-asparaginase from Penicillium cerradense

L-asparaginase (L-ASNase) is an amidohydrolase with high therapeutic value for the treatment of acute lymphoblastic leukemia (ALL). However, its clinical application is limited by immunogenicity, allergenicity, and adverse effects from glutaminase activity. In this study, we engi...