Institute of Physics

Beam-offset thermoreflectance with Bayesian optimization to measure the anisotropic thermal properties of semiconductor superlattices

The directional nature of heat conduction in semiconductor superlattices—marked by significant differences between in-plane and cross-plane pathways—poses substantial challenges for precise thermal property assessment. Conventional frequency-domain thermoreflectance (FDTR) techni...

Molecular modeling and quantum chemical calculation study of derived peptides from a Bowman-Birk inhibitor in complexes with trypsin

Abstract Context Bowman-Birk inhibitors (BBIs) are cysteine-rich proteins that inhibit trypsin and chymotrypsin proteases. Derived from soybeans, these natural BBIs have been identified as potential anticarcinogenic agents. Recent studies of the black-eyed pea trypsin/chymotrypsi...

Enhanced pozzolanic activity of microcrystalline cellulose via silane modification for cementitious composites

Abstract This study evaluated the effect of surface functionalization of microcrystalline cellulose (MCC) with tetraethyl orthosilicate (TEOS) on its physicochemical properties and the performance of cement-based microconcretes incorporating the modified material. Eleven MCC samp...

A large-scale in silico chimera-based strategy for engineering low-immunogenic L-asparaginase from Penicillium cerradense

L-asparaginase (L-ASNase) is an amidohydrolase with high therapeutic value for the treatment of acute lymphoblastic leukemia (ALL). However, its clinical application is limited by immunogenicity, allergenicity, and adverse effects from glutaminase activity. In this study, we engi...